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News, opinions and meeting coverage in allergy and immunology.

Step-Down Therapy in Severe COPD OK for Some

But patients with high eosinophilic burden need triple therapy

ACS: E-Cigarettes OK for Smoking Cessation ... with Caveats

Short period of dual use OK, if goal is to quit

Who's Still Smoking? ACS Report Highlights Most Vulnerable Adults

Reaching these smokers is 'most pressing challenge'

FDA Approves First Nebulized LAMA for COPD

Sunovion product uses proprietary delivery system

Morning Break: Antibiotics Running Out; Teen Sex Interest Drops; Children Drive to OR

Health news and commentary from around the Web gathered by the 麻豆传媒 staff

Asthma Biologic, Rally Among ATS Highlights

Attendees to organize on Capitol Hill; will also hear benralizumab phase III results

Add-On Nucala Does, and Doesn't, Reduce COPD Exacerbations

Significant benefit in METREX trial but not in METREO

Doctors Urged to Practice 'Conservative Diagnosis'

And sharing cell phone numbers is a good idea

Novel Drug Shows Promise as COPD Therapy

Inhaled p38 inhibitor reduced lung inflammation markers in early-stage study

Patient Registries See Promise and Challenges Ahead

Physician-driven registries adapt to a changing health system

FDA Okays Stiolto for COPD

Will include black-box warning about increased risk of asthma-related death.

Spiriva Cuts Flares in Heavily Treated Asthma

SAN DIEGO -- Tiotropium (Spiriva) Respimat improved lung function and cut exacerbations in severe asthma patients who had already maxed out other treatment options, pooled analysis of two phase III trials showed.

Heart Attack Signal Found for Spiriva in COPD

The TIOSPIR trial was used to support safety of the mist inhaler version of tiotropium (Spiriva) compared with dry powder, but the pooled data actually showed something else -- a heart attack signal, researchers argued.

EMTs Can Give Positive Pressure Ventilation

Out-of-hospital noninvasive positive-pressure ventilation in patients with severe respiratory distress significantly reduced rates of inhospital mortality and need for invasive ventilation, researchers found.

Yoga May Be Good for COPD

CHICAGO -- With its focus on breathing exercises, yoga may improve some of the symptoms of chronic pulmonary obstructive disease (COPD) along with boosting quality of life, researchers said here.

Cinnamon Game Harms Players

The "cinnamon challenge鈥� -- a party trick among youths who accept a dare to swallow a spoonful of ground cinnamon -- has led to a surge in calls to poison control centers with reports of spice-induced choking and aspiration, according to a new report.

Subjective Effects Drive COPD Outcomes

ATLANTA -- For patients with COPD, their own assessment of breathing problems is more predictive of outcomes than spirometry or doctor-diagnosed exacerbations, a researcher said here.

Cigarette Smoke Ups Mucus in Lungs

Cigarette smoke suppresses a protein whose normal function is to prevent an overpopulation of mucus-producing cells in the lungs, researchers reported.

Cigar and Pipe Smoking Hurts Lungs

Pipe and cigar smoking are linked to health impacts similiar to those seen with cigarette smoking, researchers found.

ATS: CPAP Effective in Mild Sleep Apnea

SAN DIEGO -- Even in patients with only mild obstructive sleep apnea, continuous positive airway pressure (CPAP) improves daily function and reduces daytime sleepiness, a researcher said here.

Eating Can Be Risky Business for COPD Patients

PITTSBURGH -- Poor coordination between swallowing and breathing in chronic obstructive pulmonary disease may increase risk of aspiration pneumonia and exacerbations, researchers warned.

CF Death Prompts FDA Alert on Nebulized Liquid Colisthemethate

ROCKVILLE, Md. -- The death of cystic fibrosis patient had led the FDA to alert physicians about the risk of prescribing premixed colistimethate for inhalation with a nebulizer.

FDA Approves Ambrisentan (Letairis) for Pulmonary Arterial Hypertension

ROCKVILLE, Md. -- The FDA has approved ambrisentan (Letairis), an endothelin receptor antagonist, for treatment of pulmonary arterial hypertension (PAH).

FDA Approves Smoking-Cessation Drug

ROCKVILLE, Md. 芒鈧€� The FDA today approved the smoking cessation drug Chantix (varenicline tartrate), which targets nicotine receptors in the brain.

High-Dose Steroids Linked to Risk of Atrial Fibrillation

ROTTERDAM, The Netherlands 芒鈧€� High dose corticosteroid therapy may increase the risk of atrial fibrillation, researchers here reported.

Antidepressant Eases Methamphetamine Addiction Symptoms

LOS ANGELES - The high and cravings of methamphetamine addicts can be reduced by the same antidepressant that helps in smoking cessation (bupropion), researchers here reported.

What a Pain! Now It's Tylenol Troubles

NOTTINGHAM, England-Acetaminophen, the popular painkiller found in Tylenol and generic analgesics, has been associated with a dose-related risk of lung disease, an effect not seen with ibuprofen (Motrin, Nuprin) and aspirin.