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News, opinions and meeting coverage in cardiology.

Billion Dollar Lab Scam: The Beat Goes On

Yet more fallout from the catastrophic bankruptcy of HDL Lab

The Lancet Versus BMJ: A Dispatch From the Statin Wars

The editors of the two top U.K. medical journals are in a bitter fight

ESC: PCSK9 Tx -- Ready for Prime Time or Still Unproven?

Debate highlights pros and cons of these cholesterol-lowering drugs

ACC: Looking Beyond Statins in LDL Lowering

New ACC guidance maps a path

Bariatric Surgery Improves Metabolic Syndrome for PCOS

Small cohort with obesity and PCOS saw improvement

How to Avoid Misdiagnosis

How a patient makes you feel may affect your diagnostic acumen

ACC: Placebo Challenge for Statin Intolerance?

Cardiologists debate whether strategy might work in the clinic too

CNN Calls Out 'Cataract Risk' in HOPE-3

Statins and cataracts: So what?

ACC: Evolocumab May Be Best Option for Statin Intolerance

Far greater LDL reduction but still some muscle complaints in GAUSS-3 trial

ACC: HOPE Results Boost Statin Prevention Role

Mortality and nonfatal events reduced

CardioBrief: New Thinking on Primary Prevention, Death, and Statins

Could lifetime benefit replace 10-year cardiovascular risk in shared decision-making?

CardioBrief: The Price of a 'Free' Copay Card? Privacy

Amgen wants 10 years of patient data for Repatha copay card

Immune Globulin: First for Severe Statin Reaction?

Small case study supports not waiting in statin-triggered autoimmune myopathy

Doctors Urged to Practice 'Conservative Diagnosis'

And sharing cell phone numbers is a good idea

CardioBrief: Dollars for Heart Docs

Analysis of CMS database shows some docs pocketed millions from drug and device makers.

Evolocumab Receives Mixed FDA Review

FDA sees strong efficacy of new injectable heart drug, but questions appropriateness of study population

CardioBreak: Modern Bloodletting, a New Statin Strategy

Recent developments of interest in cardiovascular medicine.

Mild Stenosis Linked to Death in Diabetes

Long-term registry shows impact similar to single-vessel obstruction.

Atherosclerosis a Signal for Brain Drain?

Plaque burden was linked to cognitive impairment in a population-based study.

Do Statins Up a Woman's Risk for Thyroid Cancer?

Estrogen may neutralize the cancer-protective effects of cholesterol-lowering drugs.

Morning Break: The B.O. Talk, No Love for Niacin

Health news and commentary from around the Web, gathered by the 麻豆传媒 staff.

'Bulletproof' Coffee May Hike Lipids

LAS VEGAS -- Spiking coffee with butter and coconut oil -- a concoction known as "bulletproof coffee" -- may be boosting hyperlipidemia in otherwise healthy patients, researchers said here.

Diet Rich in Beans, Lentils, Peas Lowers LDL

People who consumed a serving a day of dietary "pulses" -- beans, chickpeas, lentils, and peas -- significantly reduced their low-density lipoprotein cholesterol, a meta-analysis concluded.

Eating Before Lipid Test OK

It may not be necessary to fast before a routine cholesterol check, a large community-based population study suggested.

Cardio Notes: Sex Improves with Stenting

Opening the arteries of those with stable coronary disease also opens the door to an improved sex life. Also this week, bariatric surgery helps remodel the heart.

FDA Adds More Warnings for Lipitor, Crestor, and Zocor

WASHINGTON -- Statins may cause drug-drug interactions for patients taking drugs to treat HIV/AIDS or hepatitis C, according to a new statin warning from the FDA.

FDA Adds Diabetes Warning to Statin Label

WASHINGTON -- The FDA is changing the labeling on statins to include a warning about increased risks of hyperglycemia and transient memory problems, but the agency is no longer recommending routine liver function testing.

Fructose No Substitute for Glucose in Diabetes

NEW YORK -- Although it negates the dumping of glucose directly into the bloodstream, fructose may not be the choice sweetener for diabetics, researchers said here.

FDA Warns Against Use of High-Dose Simvastatin

The highest approved dose of simvastatin -- 80 mg -- should be used only in those patients who have already been taking it for at least 12 months without signs of myopathy, the FDA announced Wednesday.

Diet, Exercise Sufficient to Reduce Triglycerides

While cholesterol control is often balanced between statins and lifestyle changes, reducing triglycerides can usually be accomplished with diet and lifestyle changes alone, according to a new scientific statement from the American Heart Association.

Abnormal Liver Enzymes No Reason to Avoid Statins

Statins are not only safe and effective for patients with liver enzyme abnormalities but also appear to improve their liver function, researchers found.

ACC: Triglycerides Decreased with Rosuvastatin Therapy

ATLANTA -- In a study that specifically scrutinized the effects of statin therapy on triglycerides, researchers said that rosuvastatin (Crestor) significantly reduced the blood lipid that has been linked to coronary artery disease better than placebo.

ACC: FDA Announces Review of ACCORD Data

ATLANTA -- The FDA said it will conduct a full review of findings from a study which concluded that neither aggressive lipid-lowering therapy nor tight blood pressure control reduced cardiovascular events in persons with diabetes.

Ending Statins May Not End Associated Muscle Pains

Patients experiencing muscle pain and weakness as a result of statin treatment may continue to suffer symptoms long after stopping the drugs, French researchers reported.

Hidden Dangers of Herbal Meds Reviewed

Herbal medicines are not always the harmless nostrums that many patients and even some physicians think, but may actually contribute to cardiovascular morbidity and mortality, researchers warned.

Abnormal Lipid Levels Common in Teens

One in five American adolescents has unhealthy cholesterol and triglyceride levels, suggesting that targeted screening of youths would be a good idea, CDC researchers said.

ESC: Peto Analysis Called Short on Proof of Simvastatin/ Ezetimibe Cancer Safety

SEATTLE -- Simvastatin/ezetimibe (Vytorin) may increase the risk of cancer after all, concluded a leading American biostatistician who dismissed as prematurely reassuring an analysis by Richard Peto, Ph.D., F.R.S., that found the link with excess malignancy to be overblown.

AHA: Some Statins May Disrupt Sleep

ORLANDO -- If patients taking simvastatin (Zocor) develop sleep disturbances, changing statins may be a good idea, researchers suggested here.

FDA Warns Against Use of Red Yeast Rice Supplements

ROCKVILLE, Md. -- The FDA has warned consumers against using three brands of red yeast rice, a product marketed as a natural remedy for high cholesterol, because they may contain lovastatin, the active ingredient in Mevacor.

Plant Sterols Added to Orange Juice May Do the Heart Good

SACRAMENTO, Calif. -- Plant sterols added to orange juice can significantly reduce markers of cardiovascular risk, researchers here reported.

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