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Prevention

News, opinions and meeting coverage in cardiology.

Aspirin, Fish Oil Disappoint in Primary CV Prevention

Two randomized trials suggest little to no net benefit

ESC: PURE Buries Controversy, Advocates for 'Balanced Diet'

But dairy and red meat levels still differ from guidelines

ESC: Interatrial Shunting Safe in HFpEF, Pivotal Trial to Come

Device eases left-sided filling pressure, but to what clinical significance?

ESC: Short DAPT with Ticagrelor Doesn't Improve Outcomes

Antiplatelet strategy safe, but misses superiority to standard DAPT after stenting

ESC: Aspirin Holds Little Net Benefit for Primary CV Prevention

'No compelling evidence' emerges in two randomized trials

ESC: Omega-3 Supplements No Better Than Olive Oil for CV Risk

1-g dose disappoints in ASCEND trial

ESC: Weight-Loss Drug Clears Major CV Hurdle

Trial also shows modest reduction in new cases of diabetes

ESC: Rivaroxaban Doesn't Prevent VTE after Acute Illness

Efficacy shown in prior trial is lost, but safety gained in this setting

Heart Health and Dementia Risk; The End of Pap Smears: It's PodMed Double T!

This week's topics include dementia risk, the importance of serum cholesterol, Medicare's drug costs, and cervical cancer screening recommendations

ESC: CTA for Stable Chest Pain Prevents More MIs Long Term

Better than stress ECG as first-line test, SCOT-HEART investigators say

Cath Lab Recap: Intracardiac Echo; Safe Late Lumen Loss Limit

Interventional cardiology news to note

Primary Prevention Headlines at ESC

Will aspirin, fish oil pan out in big trials?

NOAC's Brain Bleed Risk Outside Afib May Be Dose-Dependent

Higher risk seen only with higher rivaroxaban doses in meta-analysis

Don't Group Afib, Atrial Flutter Together in Evaluating Stroke Risk

Same CHA2DS2-VASc score, different outcomes

Antidepressant After ACS May Help Long-Term Cardiac Outcomes

Extended trial follow-up shows advantages where prior RCTs have not

Tight BP Control Lowers Risk for Mild Cognitive Impairment

Data came from controversial SPRINT trial

Paying Cash at Walmart Often Cheaper than Medicare Copay

Heart drug analysis finds this especially with Medicare Advantage plans

Heart Diet Hype vs Heros: Seaweed, Omega-3s, Mushrooms

ACC review tackles what clinicians should know on trendy foods

How Bad Are Sleep Problems for Hospital Patients?

Pretty bad, say Dutch researchers, but fixable with "simple changes" in nightly routines

Fecal Occult Blood Flags Risks Beyond Colon Cancer

Positive FOBT tied to increased mortality from non-cancer causes

CV Risk in RA: Questions Remain

TARGET study should fill in the clinical gaps

Afib Patch Test; Heart Failure and Genetics: It's PodMed Double T!

This week's topics include a patch to diagnose atrial fibrillation, USPSTF recommendations on nontraditional risk factors for heart disease, the role of genetics in congestive heart failure, and multivitamins and heart disease.

SGLT-2 Inhibitors Tied to Lower All-Cause Mortality Risk

Head-to-head comparison with DPP-4 inhibitors also showed heart protection

Intensive Treatment Doesn't Cost More

Therapy aimed at treating all organ targets extends life

Meds Improve Cardiovascular Risk in RA

Benefits seen for hydroxychloroquine, methotrexate, and tocilizumab

Key Mediterranean Diet Trial Retracted

But republished results show same advantage after excluding protocol violations

A Better LDL Calculation Method

Friedewald lowballed lipids; Martin/Hopkins was on par with lab reference

Euro, U.S. Hypertension Guidelines Not So Different

BP guideline guru Suzanne Oparil, MD, weighs in

Europe Stands Pat on Hypertension Thresholds

ESC doesn't follow ACC/AHA on diagnostic cutoff, focuses on control rates

Why Does Anyone Still Eat Egg Whites?

Ovophiliac Anthony Pearson, MD, likes some recent studies

Aspirin Appears Protective in COPD Patients

Too early for recommendations, but rate of 'moderate acute' exacerbation was reduced

Carvedilol Helps Protect Heart During PPGL Surgery

Med offers superior blocking for cardiac complications in pheochromocytoma

Study: Hospitals Overuse VTE Prophylaxis

65% of patients in non-ICU wards in Michigan got more than recommended

Hypogonadal Men See Better Heart Health on Testosterone Tx

Fewer deaths due to MACE seen over 10 years versus controls

Genetics Identified for Alcohol-Related Heart Damage

Variant in titin-coding gene may contribute to cardiomyopathy susceptibility

Low NOAC Adherence Worse Than Taking Warfarin?

Higher thromboembolic risk seen in observational data

Ticagrelor Linked to Sleep Apnea, Dyspnea

Breathing problems particularly common with this particular antiplatelet

LAA Closure Device Thrombi 'Not Infrequent,' May Cause Strokes

Timing suggests causation in at least half of strokes with device-related thrombi

Trial: Don't Wait for Pacing in Syncope with Bifascicular Block

Lower event risk seen than with watching loop recorder feedback first

CABANA Misses Primary But May Spur Afib Ablation Anyway

Per protocol, ITT analyses differed on advantage for hard clinical endpoints

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