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News, opinions and meeting coverage in cardiology.

A box of colchicine 500 mg tablets

Colchicine Shows Promise in COVID-19 Patients, With Caveats

Clinical effects need further investigation, authors urge

A box of Xarelto 10 mg tablets

Could Extended Anticoagulation Help After COVID-19?

Trial analysis of post-discharge patients is suggestive for pandemic care

A computer rendering of acute respiratory distress syndrome caused by the coronavirus

Autopsies Turn Up Strange Feature of COVID-19 Lungs

Study finds more thrombi and a new puzzle in the vessels

Vials of remdesivir

Remdesivir Safety Forecast: Watch the Liver, Kidneys

Data remain sparse, but a few risks are emerging

A medical illustration of a pulmonary embolism

COVID-19 Pulmonary Embolism Often Seen Outside the ICU

Majority of Detroit hospital system's cases didn't require ICU-level care

An illustration of a blood clot

Anticoagulation Guidance Emerging for Severe COVID-19

Pragmatic choices dominate as guidelines are shaping up

DOAC Works in Cancer-Related VTE, No Tradeoff in Bleeds

Apixaban monotherapy matches dalteparin in non-inferiority trial

An Asian man from the YouTube video next to an MRI of a human body

73 Hours of Video Games = Total Organ Collapse

Gamer's sitting leads to serious consequences

The packaging and bottle of Eliquis

Eliquis vs Xarelto: Which Is Better in Afib?

One DOAC shows better safety, efficacy in U.S. cohort study

SOLD OUT over a vial of Heparin

How to Handle a Heparin Shortage: Effective Strategies

With supply chain issues in China, it's a real threat, group says

ASH over a photo of Orange County Convention Center, Orlando, FL

Study: Adding Aspirin to DOAC? Better Have a Good Reason

Combination tied to marked increase in bleeding risk

ASH over a photo of Orange County Convention Center, Orlando, FL

Study Bolsters Case for Novel Xarelto Formulation for Kids

Pharmacokinetic data indicate appropriate dosing schemes across wide range of weight categories

A bottle of Xarelto over a computer rendering of a blood clot

DOAC Disappoints in Thrombotic Autoimmune Disorder

Drug may, in fact, pose serious risks in this population

Enoxaparin May Be Underdosed for CRC Surgery Patients

Standard dose yielded low anticoagulation levels in 68% but no increase in venous thromboembolism

Doing Shoulder Surgery in Denver (or La Paz)? Read This

40-fold (!) increase in 30-day pulmonary embolism risk with procedures performed at high altitude

Visual Guide to AVERT's VTE Prevention in Cancer

Apixaban effective against important chemotherapy side effect

Cancer-VTE Trial Falls Short

High dropout rate undermines rivaroxaban prophylaxis trial

LMWH Prevails for VTE Prevention in Guideline

ASH unveils first six chapters of comprehensive recommendations

ESC: Rivaroxaban Doesn't Prevent VTE after Acute Illness

Efficacy shown in prior trial is lost, but safety gained in this setting

Post-Op VTE Risk Up After Intra-Op Blood Transfusion

Deep vein thrombosis, pulmonary embolism more common within 30 days

Study: Hospitals Overuse VTE Prophylaxis

65% of patients in non-ICU wards in Michigan got more than recommended

Thrombectomy Takes Away Need for Lytics in PE

Favorable results with FlowTriever system in FLARE study

Novel Drug Reverses Anticoagulation in Emergencies

Andexanet stops 90% of action of factor Xa inhibitors

AHA: Brief NOAC Interruption Safer Than Warfarin in Afib Ablation

Fewer major bleeds than with uninterrupted warfarin in Japanese trial

ACC: Even Very Low Dose Rivaroxaban Prevents Recurrent VTE

Results from EINSTEIN CHOICE point to new clinical pathway

2010: When IVC Filter Use Started Going Down

FDA warning apparently made impact

After Brain Bleed, Anticoagulant Restart May Help Regardless of Subtype

Lobar and nonlobar cases both had better outcomes in meta-analysis

Um, Excuse Me, Why Did You Stop My Post-Op Anticoagulant?

Cardiology writer learns firsthand about real-world practice

AHA: Study Finds Celebrex Safe for Heart

But naproxen not as heart safe as believed

ESC: NOAC Reversal Agent Effective in Study

But results may not sway FDA

Compression Stockings; Stroke Prevention; Stents and Meds

Cardiovascular Daily wraps up the top cardiology news of the week

Aspirin Before Cardiac Surgery: Not Harmful, But Not Helpful

Death, thrombotic complication, and bleeding risk all unaffected in ATACAS trial

Patient Registries See Promise and Challenges Ahead

Physician-driven registries adapt to a changing health system

CardioBrief: Dollars for Heart Docs

Analysis of CMS database shows some docs pocketed millions from drug and device makers.

CardioBreak: Modern Bloodletting, a New Statin Strategy

Recent developments of interest in cardiovascular medicine.

Missed Doses Cripple Postop DVT Prevention

Missed doses of prophylactic anticoagulation account for much of the deep vein thrombosis that occurs in surgery and trauma patients, a study showed.

Xarelto Gets a No for Stent Thrombosis

SILVER SPRING, Md. -- The FDA has rejected an application for a new indication allowing rivaroxaban (Xarelto) to be used to reduce the risk of stent thrombosis in patients with acute coronary syndrome.

Extended Apixaban Stops VTE Recurrence

ATLANTA -- Apixaban taken for an additional year after standard venous thromboembolism (VTE) treatment reduced recurrent events in a placebo-controlled trial, researchers said.

Fainting in PE Signals High Risk

ATLANTA -- Patients with pulmonary embolism brought to emergency rooms because they had passed out tended to have the most ominous risk factors for poor outcomes, a researcher said here.

FDA Warns of Clot Risk with Yaz, Other OCs

Labels for oral contraceptives that contain drospirenone will now note that studies have shown up to a threefold increased risk of blood clots compared with other birth control pills.

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