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Type 2 Diabetes

News, opinions and meeting coverage in endocrinology.

Cancer Risk Forces Actos Off French, German Markets

Drug regulators in Germany and France have ordered doctors to stop prescribing the type 2 diabetes drug pioglitazone (Actos), following a French study suggesting a heightened risk of bladder cancer.

Diet, Exercise Sufficient to Reduce Triglycerides

While cholesterol control is often balanced between statins and lifestyle changes, reducing triglycerides can usually be accomplished with diet and lifestyle changes alone, according to a new scientific statement from the American Heart Association.

Take Rosiglitazone Off the Market, Says FDA Staff

WASHINGTON -- Rosiglitazone (Avandia) should be pulled from the market because of the "serious" cardiovascular risk the diabetes drug poses, which exceeds that of competitor pioglitazone (Actos), FDA staff reviewers again recommended.

ACC: FDA Announces Review of ACCORD Data

ATLANTA -- The FDA said it will conduct a full review of findings from a study which concluded that neither aggressive lipid-lowering therapy nor tight blood pressure control reduced cardiovascular events in persons with diabetes.

Stinky Diabetes Drug May Result in Poor Adherence

An immediate-release form of the antidiabetic agent metformin has a dead fish odor that may cause patients to stop taking the drug, clinicians warned.

FDA Finds Oral Insulin Spray Safe for IND Use

The FDA approved Oral-lyn, an insulin spray treatment for type I and type II diabetes, for its Investigational New Drug program.

Kidney Disease Raises Risk of Hypoglycemia

WHEELING, W.Va. -- Dangerous hypoglycemic episodes are a significant risk for patients with chronic kidney disease, whether they have diabetes or not, researchers said.

Weight-Loss Trial Final Report: 52 Pounds of Fat Melted Away

WEST PALM BEACH, Fla. -- The official results are in: My ending weight was 231 pounds -- a loss of 52 pounds from my starting weight of 283 pounds in January 2008.

Pregnancy Risks Differ for Interracial Couples

STANFORD, Calif. -- The risk for some pregnancy complications may be greater when one partner is white and the other Asian, researchers found.

Normal Enzyme Levels May Hide Advanced Liver Fibrosis

MILAN, Italy -- Patients with nonalcoholic fatty liver disease but normal alanine aminotransferase (ALT) levels are still at risk of severe hepatic disease, researchers found.

Herpes Virus Linked to Ketosis-Prone Diabetes

PARIS -- A herpes virus is associated with an atypical form of type 2 diabetes found in people of African origin, researchers said here.

Boxed Heart Failure Warning Added to Two Diabetes Drugs

ROCKVILLE, Md. -- The makers of rosiglitazone (Avandia) and pioglitazone (Actos), have agreed to add a black box warning to the type 2 diabetes drugs' labels about an increased risk of heart failure, the FDA said today.

FDA Approves 'Gila Monster' Diabetes Drug

ROCKVILLE, Md.-The FDA announced today it has approved a new injectable diabetes drug synthesized from gila monster saliva, but says the drug should only be used in combination with older oral medications.