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FDA's Warning on SGLT-2 Inhibitors; Diet Battles; An Avocado A Day?

— News and commentary from the endocrinology world

MedpageToday

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The FDA issued a this week regarding the risk of a rare but serious genital infection, also known as Fournier's gangrene, associated with the use of SGLT-2 inhibitors.

Boys whose testes do not descend as kids may face a higher and testicular cancer later in life. "Early surgery can reduce the risk of malignancy and male infertility, and ultimately has the potential to reduce future adult male reproductive disorders," said senior study author Natasha Nassar, PhD, of the University of Sydney, in a statement. (The Lancet Child & Adolescent Health)

The benefits of the extend to older people. "The more you follow the Mediterranean diet, the greater the gain in terms of mortality risk reduction," said study author Licia Iacoviello, MD, PhD, of the University of Insubria in Varese, Italy, in a statement. (British Journal of Nutrition)

However, the PURE study backed a balanced diet of fruits, vegetables, dairy, red meat, and some fat and carbs as the healthiest diet in the world, in data presented at the European Society of Cardiology meeting this week. Catch up on all of 鶹ý's ESC coverage here.

U.K.-based KaNDy Therapeutics just finished raising over $32.5 million (£25M) for the phase IIb trial of their , which works by blocking neurokinin-1 and -3 receptors. (FierceBiotech)

In other menopause news, researchers discovered that older female also experience the life change just like humans do. (The Independent)

The FDA declined to approve the antisense drug volanesorsen for , sending a Complete Response Letter to drugmakers Akcea and Ionis. An advisory panel had voted narrowly in favor of approval back in May. (Reuters)

Researchers from Tufts University are recruiting participants to see if eating for 6 months can help with loss of belly fat. (HuffPost)

Obesity may prevent the body from repairing and subsequently building muscle after . (Journal of Physiology)

  • author['full_name']

    Kristen Monaco is a senior staff writer, focusing on endocrinology, psychiatry, and nephrology news. Based out of the New York City office, she’s worked at the company since 2015.