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General Endocrinology

News, opinions and meeting coverage in endocrinology.

Low Preop Sodium Raises Mortality Risk

Preoperative hyponatremia significantly increased the risk of 30-day postsurgical mortality, a risk that extended across all subgroups of surgical patients, investigators reported.

NAMS Founder: WHI Wrong on HRT

A leader of the North American Menopause Society wants an independent review of all major publications from the Women's Health Initiative.

Vitamin D Test Accuracy Called into Question

HOUSTON -- Two widely used tests to determine vitamin D status produced results that exceeded the allowable limits for error in at least 40% of cases, according to a study reported here.

Big Breakfast, Plus Dessert Aids Weight Loss

HOUSTON -- Obese adults lost significantly more weight by starting the day with a calorie-and carbohydrate-heavy breakfast that included a sweet treat, instead of saving more calories for dinner, according to a study reported here.

Testosterone Tx Helps Obese Men Trim Waistline

HOUSTON -- Obese hypogonadal men lost an average of 36 pounds during long-term testosterone replacement therapy, results of a prospective cohort study showed.

Lymphedema Tied to Obesity

Obesity may contribute to the development of lymphedema, a small study showed.

Prolia Linked to Serious Skin Side Effects

RALEIGH, N.C. -- More than 40 serious cutaneous adverse events linked to the osteoporosis formulation of denosumab (Prolia) were discovered in a review of FDA records, investigators reported here.

FDA Adds Diabetes Warning to Statin Label

WASHINGTON -- The FDA is changing the labeling on statins to include a warning about increased risks of hyperglycemia and transient memory problems, but the agency is no longer recommending routine liver function testing.

Fructose No Substitute for Glucose in Diabetes

NEW YORK -- Although it negates the dumping of glucose directly into the bloodstream, fructose may not be the choice sweetener for diabetics, researchers said here.

RSNA: Growth Hormone May Help Heavy Women With Bone Problems

CHICAGO -- Premenopausal women who are obese may not be spared from osteopenia, as some research has suggested, but growth hormone therapy may help spur bone formation, researchers said here.

FDA Approves Testosterone Gel Applied to Thigh

A topical testosterone gel designed to be applied to the upper leg has won FDA approval for use by testosterone-deficient men, its manufacturer said.

SSRIs Affect Breast Milk Production

Women taking selective serotonin reuptake inhibitor antidepressants may experience delays in postpartum milk production, researchers said.

Adrenal Suppression From Topical Corticosteroids Surprisingly High

GAITHERSBURG, Md.-Adrenal suppression affects 30% to 80% of users of prescription topical corticosteroids, according to data presented at an FDA advisory panel meeting. The session was convened to discuss taking prescription topical corticosteroids over the counter.