New Standard for Unresectable Hepatocellular Carcinoma? Adding durvalumab and bevacizumab to transarterial chemoembolization almost doubles PFS Jan 21, 2024
HAIP Chemo Offers OS Advantage in Advanced Intrahepatic Cholangiocarcinoma One in three trial patients still alive at 3 years after hepatic arterial infusion pump treatment Jan 20, 2024
Radioligand Gets Big Win in High-Grade GEP Neuroendocrine Tumors Lutetium dotatate reduces PFS risk by 72% in randomized trial Jan 20, 2024
Adding Immunotherapy, Anti-TIGIT in First Line Boosts OS in Esophageal Cancer But how much did investigational tiragolumab contribute to efficacy? Jan 19, 2024
Long-Term Data Affirm First-Line Immunotherapy for Advanced Esophageal Cancer Three times as many patients alive at 5 years with chemo plus pembrolizumab Jan 19, 2024
First-Ever Experiment Shows How Pigs Could One Day Help Liver Failure Patients Penn surgeons externally attached gene-edited pig liver to brain-dead human Jan 19, 2024
Subclasses of Steatotic Liver Disease Can Help Determine Prognosis Risk of liver decompensation increased progressively when alcohol intake came into play Jan 18, 2024
Linaclotide Doubled Bowel Movements in Children With Functional Constipation Pivotal phase III data also showed improvements in other symptoms Jan 12, 2024
ACIP Unveils Its 2024 Adult Immunization Recommendations Schedule must be more user-friendly to improve vaccine uptake, critics say Jan 11, 2024
Vaccine 'Promising' for Delaying Relapse in KRAS-Mutated Pancreatic Cancer, CRC T-cell response linked to 86% reduced risk of relapse, death Jan 09, 2024
Clinical Challenges: Integrating Diet Into Crohn's Disease Management Whole-foods dietary patterns should complement therapeutic regimens Dec 27, 2023
Rectal Botox Injections Improved Fecal Incontinence, Urgency "Study represents an important step forward in the field," editorialist says Dec 22, 2023
Homelessness Tied to Worse Cancer Outcomes Among Veterans However, all-cause mortality rates in lung, colon cancer lower versus other healthcare settings Dec 21, 2023
Ozanimod Did Not Appear to Lead to More Adverse Pregnancy Outcomes However, avoiding pregnancy when on the IBD/MS drug still advised Dec 19, 2023
'Curable': A Case for Precision of Language Patients need a clear description of their prognosis Dec 19, 2023
Novel Oral Agent May Dial Down Ulcerative Colitis Severity Investigational drug missed primary endpoint, but yielded durable responses in early trial Dec 18, 2023
Shingles Vaccine Reduced Zoster Attacks in Patients With IBD Patients 50 and older saw benefits with vaccine, except in cases of complicated zoster Dec 18, 2023
Goodbye, Appendix. Hello, Crohn's Disease? Meta-analysis finds a possible connection, although high heterogeneity was an issue Dec 17, 2023
Red Meat Consumption Tied to Higher Chance of UC Flare But similar association not seen for other high fat foods Dec 17, 2023
National Database Study Finds Higher Risk for Barrettβs Esophagus in IBD But no greater chance of BE-tied malignancy for these patients Dec 16, 2023
Lenvatinib-Pembrolizumab Combo Misses Goal in First-Line HCC Trial Numerical advantages in OS, PFS fall short of statistical significance Dec 13, 2023
Recurrence Rate of Colorectal Adenomas Reduced With Endoscopic Submucosal Dissection However, more adverse events occurred compared with endoscopic mucosal resection Dec 11, 2023
EUS-Guided Gastroenterostomy Better Option for Cancer-Related Duodenal Blockages However, technique and technology are not widespread Dec 08, 2023
GLP-1 Drugs Linked to Lower Colorectal Cancer Risk for Diabetes Patients Association strongest in patients with overweight, obesity Dec 07, 2023
Two-Week Prophylaxis May Prevent Hep C After Kidney Transplant Direct-acting antiviral prophylaxis worked in all 10 cases in pilot trial Dec 01, 2023
Methotrexate Tied to Greater Risks for Older Patients With CKD FDA should consider warning labels based on study results, researchers argue Nov 28, 2023
Stephen Colbert Has Surgery for Ruptured Appendix Recent studies have focused on whether appendicitis can be managed with antibiotics alone Nov 28, 2023
Biologic Therapy for IBD Not Tied to Higher Risk of Major Heart Events Newer agents also associated with lower VTE risk versus non-advanced treatments Nov 28, 2023 video
Chemoimmunotherapy Improves Pathologic Outcomes in Gastroesophageal Carcinoma Adding atezolizumab to FLOT led to more downstaging, complete regressions versus chemo alone Nov 24, 2023
Two Approaches for Infected Necrotizing Pancreatitis Go Head-to-Head Upfront endoscopic necrosectomy wins out on reinterventions, time to clinical improvement Nov 24, 2023
Mahvash Disease Case Resolved With Liver Transplantation Rare disease should be part of the differential in the presence of massive pancreaticomegaly Nov 22, 2023
How to Position the Growing Number of Therapies in IBD "Exciting time" to treat Crohn's disease and ulcerative colitis, expert says Nov 21, 2023 video
Silent Gastrointestinal Bleeds Track With Antiplatelet Choice After PCI OPT-PEACE captured serial changes in gastrointestinal tract injury prior to overt bleeding Nov 17, 2023
PPAR Agonist Led to 'Clinically Meaningful' Improvement in PBC-Related Pruritus Seladelpar also improved markers of disease activity versus placebo Nov 15, 2023
Novel MASH Drug Reduces Liver Fat in Mid-Stage Trial At highest dose, thyroid hormone receptor-beta agonist decreased liver fat content by 45% Nov 15, 2023
New Guselkumab Responses in Ulcerative Colitis Emerge After 12 Weeks More than half of patients not in early clinical response at week 12 responded by week 24 Nov 14, 2023 video
Emergency Liver Transplant Effective for Severe Acute-on-Chronic Liver Failure 1-year survival reached 78% for patients who received an emergency transplant Nov 14, 2023
Novel Drug Makes Its Case for Pretreated Primary Biliary Cholangitis In randomized trial, oral elafibranor induced biochemical response at 1 year in 51% of patients Nov 14, 2023
Diabetes Linked to Higher Colorectal Cancer Risk Associated risks highest in those with recent diagnoses Nov 14, 2023
AKI Response Tied to Improved Survival for Patients Waiting on Liver Transplant Results highlight the importance of prompt recognition and treatment of acute kidney injury Nov 13, 2023
