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General Geriatrics

News, opinions and meeting coverage in geriatrics.

Inhaled Levodopa May Bridge Parkinson's 'Off' Periods

Inhaler eased breakthrough motor symptoms between standard levodopa doses in an early study

One Proteasome Inhibitor Tops Another in Relapsed Myeloma

Progression-free survival doubled with carfilzomib versus bortezomib

PFS Rises in Progressive Myeloma with Targeted Biologic

Adding elotuzumab boosts median progression-free survival by almost 5 months.

13 Apple Watch Medical Apps Made for Physicians

Even though there are over 3,500 apps that have been customized for the Apple Watch, there are few that health providers can actually utilize for themselves

ASCO: Annual Meeting Emphasizes Advances, Challenges in Cancer

Largest program to date highlights developments in breast cancer, other malignancies

ASCO: Chemo-ADT Combo Still Winning in Prostate Cancer

Yet another report of survival improvement with upfront docetaxel plus hormonal therapy.

Novel Drug for Cramping Shows Promise in Early Trial

Could benefit patients with MS spasticity and cervical dystonia.

Allopurinol Doesn't Worsen Acute Gout Attacks

Worries that it might prove unfounded in randomized trial.

New Rx Protocol Improves Knee Replacement Recovery

Total knee arthroplasty patients back on feet sooner with new approach to pain management.

Fat-Lysing Agent Makes Double Chin Disappear

Consistent results seen with injection of synthetic deoxycholic acid compound.

Seeds Top EBRT as Boost Tx in Prostate Cancer

And other advances in prostate cancer care from the Genitourinary Cancers Symposium.

Morning Break: Penis Reduction? Patient Suffering

Health news and commentary from around the Web, gathered by the 麻豆传媒 staff.

Predicting Death in Advanced Cancer

Study offers clues to guide clinicians, families about end of life.

5 Steps in Talking With Patients About Alternative Medicine

Ask, explain, respect, collaborate, compromise.

More Drugs, Better Survival in Metastatic Colon Cancer

Addition of oxaliplatin to FOLFIRI and bevacizumab doubled 5-year survival.

'Generic' Colchicine to Hit Market

May provide some price relief for gout patients.

Meniscus Lesions Tied to Neuropathic Pain in Knee OA

Meniscal extrusion on MRI significantly associated with increasing pain scores in knee osteoarthritis.

Women, Blacks at Greater Risk for Bunions

Subgroups most likely to develop hallux valgus confirmed in major study.

FDA Advisers Tackle Epidural Steroid Shots

Focus on adverse neurologic effects.

Gout May Protect Against Alzheimer's Disease

Study showed AD incidence higher over 5 years for patients without gout.

Osteonecrosis of the Jaw Is Rare With Denosumab for Bone Loss

Study finds risk very low, even with long-term drug therapy.

Clinical Focus In Renal Cell Carcinoma: Clues from Gene Studies

Mutations in four genes appear to play a key role in the origin of renal cell carcinoma.

Patients Should Share Accountability for Own Health

A new report recommends doctors not be penalized for poor outcomes if patients fail to follow recommended protocols

Healthcare Serial Killings Down in U.S. but Up Globally

Electronic health records may be a deterrent.

Emanuel: Did I Say Die at 75?

Death at age 75 was a "slightly random number," but Ezekiel Emanuel will just say No to statins, antihypertensives, and antibiotics after age 75.

Excerpt From 'Being Mortal ... '

Ivan Ilyich isn't as foreign to today's medicine as we imagine.

Counterpoint: Too Young to Die

Brant S. Mittler, MD, JD, thinks Ezekiel Emanuel is a dangerous man.

Shingles Risks Similar for the RA Biologics

The risk of developing herpes zoster was similar among older patients with rheumatoid arthritis (RA) treated with the various different biologic agents, a retrospective study found.

High Urate? Get Moving, Study Finds

Regular exercise significantly lessened the excess mortality risk associated with elevated serum uric acid, a large Taiwanese study found.

HTN May Halt Dementia in Very Elderly

COPENHAGEN -- Among individuals who developed hypertension at age 90 or later, their risk of also developing dementia was dramatically lower than other very elderly people whose blood pressure remained normal.

FDA: No Clear Sign of Harm With Olmesartan in Diabetics

The evidence linking use of the angiotensin II receptor blocker (ARB) olmesartan in patients with diabetes and increased cardiovascular risk is not conclusive, according to a completed FDA safety review.

ASCO: Myeloma Study Results Inconclusive

CHICAGO -- A trial comparing two immunomodulatory regimens for myeloma failed to demonstrate noninferiority for the newer drug.

ASCO: Combo Extends PFS in Relapsed Myeloma

CHICAGO -- Progression-free survival in relapsed/refractory myeloma increased significantly in patients treated with a three-drug regimen that included panobinostat versus a two-drug regimen, a randomized trial showed.

FDA Slashes Starting Dose for Lunesta

SILVER SPRING, Md. -- Patients starting on the sleep drug eszopiclone (Lunesta) should take no more than 1 mg at bedtime -- one-third the current label-recommended dose -- because of the risk of next-day impairment, the FDA said Thursday.

Shingle Risk High in Lupus, RA, COPD

Patients with autoimmune diseases and certain other chronic conditions are at increased risk for herpes zoster, a U.K. case-control study found.

Murder: Another Ambien Side Effect?

NEW YORK CITY -- Forensic psychiatrists are facing new challenges with murders committed by people under the influence of the sleep drug zolpidem (Ambien) -- not least to persuade the criminal justice system to take their conclusions seriously.

Aspirin: FDA Says 'No' Others Say 'Yes'

The FDA issued a message to consumers stating that the evidence does not support the "general" use of aspirin for the primary prevention of heart attacks and strokes.

Humans Beat Stroke Scales for ICH Prognosis

PHILADELPHIA -- Physicians and nurses in stroke units more accurately predicted outcomes in patients with intracerebral hemorrhage (ICH) compared with common prognostic scales, a researcher reported here.

How To Get Medicare To Cover A Spa Trip

Good news for doctors who think their patients need a trip to the spa: Medicare will reimburse, with only two catches.

Urine Test Can Uncover BP Med Adherence

A simple urine test might help clinicians figure out whether their patients aren't responding to antihypertensive therapy because of true resistance or because of nonadherence, a small study suggested.

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