Dual Checkpoint Blockade With Some Chemo Boosts OS in NSCLC Nivolumab-ipilimumab with two cycles of chemotherapy improved survival, regardless of histology or PD-L1 status Oct 17, 2020
Positive Anti-PD-1 Data in Gastric, Esophageal Cancer Better OS, PFS with nivolumab, pembrolizumab in advanced/metastatic disease Sep 23, 2020
Immunotherapy Falls Short Again in Ovarian Cancer No PFS benefit in advanced disease with addition of atezolizumab to chemo, bevacizumab Sep 23, 2020
No Luck for Chemo-Free Tx in First-Line Bladder Cancer Durvalumab alone or with tremelimumab no better than chemotherapy Sep 22, 2020
No Benefit With Anti-PD-L1 Drug in Metastatic TNBC Lack of progression-free, overall survival boost with atezolizumab contrast with prior trial Sep 22, 2020
Skip Chemo for Older Patients With HER2+ Breast Cancer? Less than one-month survival loss at 3 years with trastuzumab monotherapy Sep 18, 2020
Raising the Bar for Myelofibrosis Therapy Development Rational combinations, new targets, and a first-ever phase III trial with a survival endpoint Sep 14, 2020
New Insights Into Radiation-Induced Hair Loss Total dose and fraction size matter, minoxidil may spur regrowth Aug 05, 2020
Triplet OK'd as First-Line Therapy in Melanoma Immunotherapy plus targeted combo nets FDA approval in BRAF-mutant population Jul 31, 2020
Alex Trebek, Harry Reid and Their Pancreatic Cancer Treatment Exploring a 'triangle offense' against the disease Jul 28, 2020
Survival Effect of pCR Elusive in Breast Cancer 80% lower risk of recurrence with surrogate endpoint, but link to survival unproven Jul 23, 2020
Older Age Should Not Rule Out Chemo in Breast Cancer Patients Providers should consider patient priorities when discussing treatment Jul 17, 2020
Brief Quasi-Fasting Diet Boosts Breast Cancer Chemo Response Randomized trial in neoadjuvant setting Jun 28, 2020
New Standard for Relapsed/Refractory Multiple Myeloma? Triplet regimen significantly extended median PFS versus doublet in IKEMA study Jun 15, 2020
Second Surgery Gets OS Win in Recurrent Ovarian Cancer Survival improved by nearly 8 months with cytoreductive surgery at first relapse Jun 02, 2020
Early Palliation: Boon for AML Patients on Intensive Chemo Intervention led to marked improvements in QoL, mental distress, end-of-life care Jun 02, 2020
New First-Line Standard in Metastatic Bladder Cancer "High bar to beat" as avelumab maintenance improves median survival by over 7 months May 28, 2020
Avelumab Flops Again in Ovarian Cancer Another negative phase III trial, now in the first-line setting May 19, 2020
Five Days of G-CSF Adequate for Breast Cancer Chemo Rate of chemotherapy-induced febrile neutropenia similar to 7- to 10-day regimen May 08, 2020
Honing Chemo Use in Small Breast Tumors Clearest survival benefit for 8-10 mm tumors in HR/HER2-positive disease May 03, 2020
Add-On Metformin No Help in Advanced Endometrial Cancer Trial highlights deep racial disparities in treatment response, survival outcomes Apr 27, 2020
Herceptin Boosts OS in HER2-Positive Uterine Cancer New data bolster targeted approach for aggressive tumor type Apr 24, 2020
DOAC Works in Cancer-Related VTE, No Tradeoff in Bleeds Apixaban monotherapy matches dalteparin in non-inferiority trial Mar 29, 2020
CRC: Upfront, Re-Introduction of FOLFOXIRI Most Effective, but at What Cost? Modest survival improvement comes with side effects, toxicity even in healthiest patients Mar 13, 2020
Bringing Transplant to More Patients With AML Conditioning with radiolabeled antibody leads to successful transplantation in 84% of older patients Feb 25, 2020
Myeloablative Therapy Prevails in AML Transplant Study Better survival, fewer relapses compared with reduced-intensity conditioning Feb 21, 2020
Shannen Doherty's Stage IV Breast Cancer "Beverly Hills, 90210" star says she's "petrified" Feb 20, 2020
Bell Ringing Not So Joyous for Cancer Patients? Greater treatment-related distress for those who rang bell at end of treatment Feb 10, 2020
Bad News on Anti-HER2 Heart Effects Exercise, however, may help improve cardio fitness in breast cancer survivors Jan 15, 2020
Chinese Herbal May Be Chemoprotective Against Colorectal Cancer Polypectomy patients given the supplement developed fewer colorectal adenomas Jan 13, 2020
Higher Risk of Shingles Seen in Patients With Certain Cancers Vaccine development may help with prevention of herpes zoster in this population Dec 31, 2019
PD-1 vs PD-L1 Inhibitors: Do Outcomes Differ? Meta-analysis suggests they aren't equivalent Dec 27, 2019
Anti-CDK4/6 Fails to Top Chemo in HR-Positive MBC Similar PFS with chemo, palbociclib plus exemestane or fulvestrant after progression on aromatase inhibitor Dec 13, 2019
Checkpoints Show Different Outcomes in Breast Cancer Atezolizumab misses complete response benefit in triple negative patients Dec 13, 2019
T-DM1 Falls Short as Less-Toxic Option for Early Breast Cancer Promising efficacy but higher discontinuation rates and cost likely a deterrent Dec 13, 2019
Edging Closer to OS Benefit With Novel Anti-HER2 Drug Larger benefit with margetuximab in most common HER2 breast cancer phenotype Dec 12, 2019
New Standard for Metastatic HER2 Breast Cancer Consistent PFS, OS benefit with combination including oral HER2 inhibitor tucatinib Dec 11, 2019
Survival Bump With Oral AML Maintenance Ten-month OS gain, doubling of RFS with oral azacitidine in transplant-ineligible patients Dec 10, 2019
Docetaxel First May Boost Survival in mCRPC Superior outcomes observed versus approach where chemo follows newer agents Dec 05, 2019
IGHV-Unmutated CLL: Gene Signature May Predict Outcomes After First-Line FCR Prognostic tool may predict who is likely to achieve a relatively long remission Oct 15, 2019
