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Hemophilia

News, opinions and meeting coverage in oncology/hematology.

FDA APPROVED valoctocogene roxaparvovec-rvox (Roctavian) over a computer rendering of a leaking blood vessel.

FDA Gives Nod to Gene Therapy for Hemophilia A

First gene therapy approved for severe hemophilia A

Onco Break over a computer rendering of a cancer cell.

'Winners' and 'Losers'; Mandated Sick Leave and Cancer Screening; More AI Advances

News, features, and commentary about cancer-related issues

A computer rendering of a clot forming in a broken blood vessel.

Gene Tx Shows Sustained Bleeding Control in Severe Hemophilia A at 2 Years

Model predicts valoctocogene roxaparvovec could maintain mild hemophilia levels for 5 years

A computer rendering of red blood cells and platelets in a blood vessel.

New Class of Factor VIII Replacement Therapy Prevents Bleeds in Severe Hemophilia A

Weekly dosing with efanesoctocog alfa reduced annualized bleeding rate by 77%

Hemophilia in blood.

FDA OKs First Gene Therapy for Hemophilia B

Hemgenix reduced rate of annual bleeds, eliminated need for factor IX prophylaxis therapy

2022 YEAR IN REVIEW HEMOPHILIA over a computer rendering of red blood cells and platelets during hemostasis.

Year in Review: Hemophilia

Gene therapy continues to show promise in clinical trials, but is it ready for the clinic?

'Unparalleled Times' in Hematology, but Workforce Issues Persist

"This is the most exciting time ever" to be a hematologist, says ASH President Jane Winter, MD

An illustration of a physician holding a patient's hand with the text The Doctor's Art - A podcast on Meaning in Medicine

Lessons From a Lifelong Patient Turned Oncologist

Eric Winer, MD, talks about how growing up with hemophilia helped him connect with patients

ASH over a photo of the Georgia World Conference Center in Atlanta, GA.

Fitusiran Prophylaxis Cuts Bleeding in Hemophilia A/B

Monthly infusion vs on-demand bypassing agents effective in patients with or without inhibitors

FDA ADCOMM AAV Gene Therapies over a computer rendering of the liver anatomy.

Liver Toxicity in Gene Therapy Trials Could Merit Stricter Entry Criteria

FDA panel weighs in on lower vector doses and role of animal studies

A graphical representation of genome sequencing

Whole-Genome Sequencing Makes a Case in Leukemia Study

More actionable alterations detected in myeloid malignancies versus cytogenetics

ASH over a computer rendering of blood flowing through an artery

Gene Therapy Stops Bleeding in Hemophilia

Single injection had durable effectiveness, study showed

A woman with cotton in her nostrils tilts her head back and pinches the bridge of her nose to stop a nose bleed

Severe Nosebleeds More Common With Hypertension

Korean study supports link between hypertension and epistaxis

MSK Cancer Alliance: Mainly About Medicine

Bi-directional relationship strengthens regional cancer care

Combo Boosts PFS in Tough-to-Treat Myeloma

Recurrent or relapsed disease susceptible to daratumumab-bortezomib-dexamethasone