Non-Covalent BTK Inhibitor Yields High Response Rate in Pretreated CLL 73% of patients with prior exposure to covalent BTK inhibitors responded Jul 05, 2023
EphrinB2 Expression in Urothelial Cancer Tied to Checkpoint Inhibitor Activity Retrospective data confirm EphrinB2 as a negative prognostic marker Jul 05, 2023 video
I Can't Guarantee Your Next Round of Chemo Physicians face difficult conversations and decisions amid chemo drug shortages Jul 05, 2023
FDA Gives Nod to Gene Therapy for Hemophilia A First gene therapy approved for severe hemophilia A Jun 29, 2023
WHO Links Sweetener to Cancer; Younger-Age CRC Risk; PCOS and Ovarian Cancer News, features, and commentary about cancer-related issues Jun 29, 2023
TXA Holds Its Own for Heavy Menstrual Bleeding in von Willebrand Disease In phase III study, recombinant VWF not superior to cheaper alternative for type 1 and 2 cases Jun 29, 2023
Continuing Trastuzumab After Progression Shows Promise in HER2+ Gastric/GEJ Cancer Adding anti-HER2 agent to ramucirumab, paclitaxel exceeds historical PFS with doublet Jun 28, 2023
No OS Benefit With Ibrutinib in Early-Stage, High-Risk CLL Study suggests "watch and wait" should remain standard of care Jun 28, 2023
Agent Orange Exposure Tied to Bladder Cancer Risk in Veterans Increased risk described as "modest," and no association seen with aggressiveness of cancer Jun 27, 2023
PET-CT Superior to Conventional Scans for Spotting Distant Breast Cancer Mets Study shows twice as many locally advanced patients upstaged with PET-CT vs conventional staging Jun 26, 2023
Can AI Help Determine if Liver Cancer Will Respond to Standard Treatment? Early model suggests a way to predict progression-free survival Jun 26, 2023
Why Did Older Man Develop Itchy, Full-Body Rash? Here's how the medical team diagnosed and treated the rare inflammatory skin disorder Jun 22, 2023
Rates of Consent Withdrawal in Cancer Trials Low but Not 'Trivial' Factors associated with greater likelihood of withdrawal included Hispanic ethnicity, older age Jun 22, 2023
Breast Cancer Recurrence Risk Varies by Molecular Subtype Korean study suggests need for individualized surveillance, optimized use of breast MRI Jun 21, 2023
Earlier Detection of Cardiac Dysfunction Possible for Young Adult Cancer Survivors A case for monitoring global longitudinal strain despite normal LVEF Jun 20, 2023
Daily Low-Dose Aspirin Upped Incidence of Anemia in Older Adults An analysis of the ASPREE trial showed 100-mg aspirin led to more anemia events vs placebo Jun 19, 2023
Breast Cancer Drugs May Weaken Effects of Weight-Loss Drugs Survivors on aromatase inhibitors lost significantly less weight Jun 18, 2023
New Bispecific Antibody Approved for Tough-to-Treat Lymphoma Approval of glofitamab was based on a phase I/II study that showed a 56% overall response rate Jun 16, 2023
Cystic Renal Masses Often Harbor High-Grade Disease No link between grade and cancer-specific survival, active surveillance still an option for many Jun 16, 2023
Early Invasive Breast Cancer Now Leaves Mostly Long-Term Survivors Mortality risk has decreased substantially since the 1990s Jun 15, 2023
Pushback on Price Negotiation; Genetic Testing Lags; More Foreign Help for Shortages News, features, and commentary about cancer-related issues Jun 15, 2023
Base-Edited CAR-T Product 'Potent' in Relapsed Childhood T-Cell ALL One young patient achieved molecular remission within 28 days of infusion Jun 14, 2023
Pre-Existing Depression, Anxiety Tied to Worse DLBCL Prognosis Patients with depression alone had the worst overall survival Jun 13, 2023
CRISPR Therapy Exceeds Targets in Thalassemia, Sickle Cell Disease Results "indicate that exa-cel can provide a one-time functional cure," says researcher Jun 13, 2023
Breast Ultrasound Recs May Not Be Targeting the Right Women It's not just dense breasts that matter, researchers say Jun 12, 2023
CAR-T for Chronic Lymphocytic Leukemia Hits Goal of Mid-Stage Trial All patients had progressed on BTK inhibitors and most had failed venetoclax Jun 12, 2023
Hooray! A Clearer Estimate of Your Risk for Death Is Here Researchers do the legwork to incorporate smoking status into NCI's "Know Your Chances" website Jun 09, 2023
TTFields Therapy Yields OS Improvement in Second-Line NSCLC However, device was not tested alongside current standard of care, expert points out Jun 08, 2023
How Vax Skeptics Sow Doubt; Gun Death Every 11 Minutes; 90210 Star's Cancer Spreads Health news and commentary from around the Web gathered by ΒιΆΉ΄«Γ½ staff Jun 08, 2023
Studies Question Role of CDK4/6 Inhibitors in First-Line Advanced Breast Cancer No PFS, OS benefit with first-line versus second-line CDK4/6 inhibition, more toxicity, cost Jun 07, 2023
Skipping Radiotherapy 'Seems Safe' for PMBCL Patients in Remission PET-negative patients after chemoimmunotherapy fared well with observation alone Jun 07, 2023
FGFR Inhibitor Stakes Claim to Post-Anti-PD-1 Role in Advanced Bladder Cancer Survival benefit supports FGFR testing for all patients with metastatic disease, researcher says Jun 07, 2023
Checkpoint Blockade Stumbles in Advanced EGFR-Mutant NSCLC "Immediate changes" needed to patient care to avoid unnecessary toxicity, says ASCO expert Jun 07, 2023
Certain NSCLC Patients May Be Able to Stop Immunotherapy at 2 Years Retrospective study finds no difference in OS between patients who stop and those who continue Jun 06, 2023
No Survival Benefit With Immune Checkpoint Inhibitor Rechallenge in Metastatic RCC The strategy also led to increased toxicity Jun 06, 2023
New Data in NSCLC Bolster Support for Perioperative Immunotherapy EFS benefit with pembrolizumab in KEYNOTE-671, but no OS benefit "yet," says investigator Jun 05, 2023
Second-Line Axi-Cel Bests Standard in Relapsed/Refractory Large B-Cell Lymphoma The CAR T-cell therapy led to significantly longer overall survival Jun 05, 2023
New Agents for Relapsed/Refractory Myeloma Impress in Early-Stage Clinical Trials High rates of deep, durable response with bispecific antibody, rapidly produced CAR T-cell agents Jun 05, 2023
CAR-T Tops Standard Care in Heavily Pretreated Lenalidomide-Refractory Myeloma Ciltacabtagene autoleucel improved progression-free survival versus two standard triplets Jun 05, 2023
Omitting RT Safe in Many Locally Advanced Rectal Cancers Most intermediate-risk cases can be cured without pelvic radiation, says investigator Jun 05, 2023