Brentuximab Vedotin Boosts Survival in Untreated Hodgkin Lymphoma ECHELON-1 analysis showed 41% mortality risk reduction versus standard treatment Jun 21, 2022
Drugmaker Pulls Third-Line PARP Inhibitor Approval in Ovarian Cancer Decision on rucaparib follows negative OS signal and "discussions" with FDA Jun 17, 2022
MRI-Guided HIFU Effective in Intermediate-Risk Prostate Cancer QOL outcomes compared favorably with radical prostatectomy and radiotherapy, researchers said Jun 17, 2022
Xtandi During AS Reduced Progression Risk in Early Prostate Cancer Risk of disease progression cut by 46% versus those on active surveillance alone Jun 16, 2022
Early Anal Lesion Treatment Cuts Cancer Risk in People With HIV ANCHOR data support screening and treatment for anal HSIL in those ages 35 and up Jun 15, 2022
Harms of Cancer Blood Tests? FTC Healthcare Crackdown: More Smoke Than Fire? This past week in healthcare investigations Jun 15, 2022
Lorlatinib Reduces CNS Progression in ALK-Positive NSCLC Post-hoc analysis of CROWN trial does find more central nervous system toxicity, however Jun 14, 2022
Does Ditching Cost-Sharing Boost Follow-Up Colonoscopy? States saw differing results with policies eliminating costs after a positive noninvasive test Jun 14, 2022
Studies Reinforce Prognostic Role for Circulating Tumor Cells in Myeloma At higher levels, different cutoffs show at least a doubling of PFS, OS hazard ratios Jun 13, 2022
Diabetes Threatens Long-Term Survival in Metastatic Breast Cancer 5-year survival rates were not affected, however Jun 13, 2022
FDA Panel Backs Gene Tx for Degenerative Brain Disorder in Kids Advisers unanimously recommend approval for pediatric ALD patients without HLA-matched donors Jun 10, 2022
Something Fishy About Tuna and Melanoma Risk Higher total fish intake linked with 22% higher risk of malignant tumors Jun 09, 2022
P53 Antagonist Shows Early Activity in Advanced Liposarcoma ASCO roundup: ADC targeting CD46 slows mCRPC, molecule stabilizes effects of "hot spot" mutation Jun 08, 2022
Intensified Regimen for Metastatic CRC Fails to Improve Outcomes Combination of modified FOLFOXIRI/panitumumab also caused greater toxicity, study showed Jun 08, 2022
A Better Way to Irradiate Lethal CNS Metastases? Randomized trial makes case for proton craniospinal irradiation for leptomeningeal spread Jun 08, 2022
First-Line Anti-EGFR Extends OS in Left-Sided Colorectal Cancer "A win for a highly selected group of patients," says ASCO expert Jun 07, 2022
PARP Inhibitor Picks Up a Win in Frontline Maintenance for Ovarian Cancer Median PFS more than doubled with rucaparib after response to platinum-based chemotherapy Jun 07, 2022
Forego Radiotherapy for Women With Low-Risk Luminal A Breast Cancer? Study shows 5-year local recurrence rate of 2.3% with lumpectomy and endocrine therapy alone Jun 07, 2022
She Found Out She Had Prostate Cancer Then Eve Gammill, a transgender woman, fully embraced her feminine identity Jun 07, 2022
Targeted Combo Topples Chemo in Pediatric Glioma With BRAF Mutations ORR quadrupled, median PFS nearly tripled with dabrafenib plus trametinib in low-grade disease Jun 06, 2022
Radiation Alone May Suffice for Some Nasopharyngeal Cancer Chemotherapy adds little benefit in intermediate grade lesions Jun 06, 2022
Novel Agent Lessens Mucositis in Head and Neck Cancers IV infusion could allow more patients to complete treatment regimen Jun 06, 2022
Tiragolumab Fails in Extensive-Stage Small Cell Lung Cancer No change in survival when combined with atezolizumab and chemotherapy Jun 06, 2022
Liquid Biopsy May Save Colon Cancer Patients From Chemo Circulating tumor DNA could determine who needs more therapy Jun 06, 2022
Endocrine Switch Plus Ribociclib Active in Post-CDK4/6 Inhibitor Progression First randomized support for strategy in progressive metastatic HR+/HER2- breast cancer Jun 06, 2022
Myeloma Trial Supports 'Personalized Approach' to Upfront Transplant DETERMINATION confirms benefit in triple-therapy setting, but suggests timing can be tailored Jun 06, 2022
Complete Responses in 100% of dMMR Rectal Cancer With Neoadjuvant PD-1 Inhibition Chemo, RT, surgery avoided in short-term follow-up but study population was small Jun 05, 2022
Trastuzumab Deruxtecan Ushers in New Treatment Era for HER2-Low Breast Cancer DESTINY-Breast04 extends agent's benefits to historically tough-to-treat disease Jun 05, 2022
Will High-Dose Ifosfamide Become the Go-To Therapy in Recurrent Ewing Sarcoma? Data from European rEECur trial "are potentially practice changing," expert says Jun 05, 2022
Third-Line BTK Inhibitor Combo Doubles PFS in Follicular Lymphoma Significantly more responses, CRs with zanubrutinib-obinutuzumab versus anti-CD20 drug alone Jun 05, 2022
Capivasertib-Fulvestrant Combo Ups Survival in ER+/HER2- Metastatic Breast Cancer But benefit seems to be predominantly in patients with PI3K/AKT/PTEN pathway alterations Jun 05, 2022
Sacituzumab Govitecan Boosts PFS in Late-Line HR+/HER2- Metastatic Breast Cancer "This may be something that really changes the lives of these women for the better," expert says Jun 05, 2022
Immunotherapy Rechallenge in NSCLC Yields Overall Survival Boost Phase II trial sees "synergistic benefit" with checkpoint blockade and anti-angiogenesis Jun 04, 2022
IL-15 Agonist Impresses in Non-Muscle Invasive Bladder Cancer High response rate, 99%-100% cancer-specific survival at 2 years Jun 04, 2022
Brentuximab Vedotin-Chemo Boosts EFS in High-Risk Pediatric Hodgkin Lymphoma Combo regimen offers "a new standard for front-line therapy," researcher says Jun 04, 2022
KRAS Inhibitor Shrinks Tumors in Over 40% of NSCLC Patients Median survival surpasses 1 year in heavily pretreated population Jun 03, 2022
Bariatric Surgery Cuts Cancer Incidence, Death Risk Study looked at people with obesity who underwent two most popular procedures Jun 03, 2022
5-Year Interval for Cervical Cancer Screening Safe in HPV-Negative Women U.K. study also supports accuracy of HPV testing versus cytology Jun 03, 2022
Colonoscopy With a Computer-Aided Device Boosted Adenoma Detection Use of the device led to a 27% increase in adenomas per colonoscopy versus standard procedure Jun 03, 2022
Add-On Ibrutinib Boosts PFS in Untreated, Older Mantle-Cell Lymphoma Patients BTK inhibitor plus chemoimmunotherapy increased progression-free survival by over 2 years Jun 03, 2022
