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Hypercholesterolemia

Follow along on our guide to Hypercholesterolemia -- i.e., high cholesterol -- which can increase the risk of heart disease, stroke, and other cardiovascular problems. An estimated 40% of adults worldwide have high cholesterol, which is estimated to cause 2.6 million deaths annually and 29.7 million "disability-adjusted life years," according to the World Health Organization. Each step of the Medical Journey will delve into another aspect of the condition, including causes and diagnosis, genetic factors, related conditions, therapy options, coping strategies, and lessons learned from unique case studies -- all of which have undergone expert review. Every installment will also include a separate, downloadable, printable information resource for patients.

MedpageToday

Hypercholesterolemia: A Complex System

–Back to basics on cholesterol carriers and measurement
Illustration of the letter i on a piece of paper over a hand over a blood droplet with an upward arrow over cholesterol
Patient Handout
For Your Patients: Hypercholesterolemia: Understanding Your Diagnosis

Consequences of Hypercholesterolemia

–A deep dive into how cholesterol contributes to atherosclerosis
Illustration of the consequences of what atherosclerosis can do over a blood droplet with an upward arrow over cholesterol
Patient Handout
For Your Patients: Why Do High Cholesterol Levels Matter?

Genetics of Hypercholesterolemia

–A deep dive into the heritability of high cholesterol
Illustration of a DNA strand over a blood droplet with an upward arrow over cholesterol
Patient Handout
For Your Patients: Who Gets Hypercholesterolemia?

Case Study: High Lipoprotein(a) Levels in Younger Patients Are Not So Clear Cut

–Clinicians ponder how to advise man in his early 40s with a strong family history of premature CV events
Illustration of a written case study over a blood droplet with an upward arrow over cholesterol

The Shifting Epidemiology of Hypercholesterolemia

–Prevalence, global trends, and population-attributable risk
Illustration of infected blood droplets over Earth over a blood droplet with an upward arrow over cholesterol
Patient Handout
For Your Patients: Screening and Diagnosis of High Cholesterol

Diagnosing Hypercholesterolemia

–When and how to screen, what the diagnostic levels are, and which secondary causes to watch for
Illustration of infected blood droplets over Earth over a blood droplet with an upward arrow over cholesterol
Patient Handout
For Your Patients: Understanding Inherited Cholesterol Disorders

Primary Prevention in Hypercholesterolemia

–Risk prediction tools, risk enhancing factors, and the impact of lifestyle
Illustration of no smoking symbol, healthy food, etc over a blood droplet with an upward arrow over cholesterol
Patient Handout
For Your Patients: Daily Choices That Help Tackle Hypercholesterolemia

Case Study: Teenage Girl's Shortness of Breath and Chest Pain

–Extensive investigation was needed to unravel the complications of the condition
Illustration of a written case study over a blood droplet with an upward arrow over cholesterol

Options for Treating Non-Familial Hypercholesterolemia

–Statins, ezetimibe, PCSK9 inhibitors, bile acid sequestrants, bempedoic acid, and more
Illustration of a red slash over non-familial hypercholesterolemia over a blood droplet with an upward arrow over cholesterol
Patient Handout
For Your Patients: What About Alternative Treatments and Supplements?
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