For Better COVID Vax Response in Rheumatology Patients, Hold the MMF Longer Small study suggests at least a 10-day holiday Nov 14, 2022
Another Adalimumab Biosimilar Seems Set for Interchangeability Trial data pave way for FDA approval Nov 14, 2022
Safer Alternative to Cyclophosphamide at Hand for ILD? Drug targeting B cells as effective as broad-spectrum immunosuppressant in lung disease Nov 14, 2022
Novel BTK Inhibitor Looks Good for Sjogren's Syndrome Phase II data show good efficacy by objective measures, even with strong placebo effect Nov 13, 2022
ANCA-Associated Vasculitis: Novel Biologic Shows Promise for Replacing Steroids Small trial demonstrates big cut in steroid-linked adverse effects Nov 13, 2022
Twelve-Month Data Back Pegloticase-Methotrexate Gout Combo More support for add-on methotrexate to maintain protein drug's efficacy Nov 13, 2022
Want a Few Weeks of Knee Pain Relief? Try This Local nerve block proves mettle in randomized trial, though benefit didn't last long Nov 12, 2022
For Systemic JIA, Start Biologics Early Observational study shows excellent efficacy in systemic pediatric arthritis Nov 10, 2021
Secukinumab: An Up-and-Coming Option in Giant Cell Arteritis? Phase II trial found sustained remission with steroid-sparing effects Nov 10, 2021
Voclosporin Benefits in Nephritis Persist at 30 Months No new safety signals seen in long-term extension for lupus nephritis Nov 09, 2021
Vitamin D and Disease Prevention: Worth Another Look? Incidence of autoimmune disease decreased by 25-30% with dietary supplements Nov 08, 2021
Guselkumab Response Durable in Psoriatic Arthritis Skin and joint improvements persisted through 2 years of follow-up Nov 08, 2021
Early Biologics Better in Juvenile Idiopathic Arthritis After 2 years, more patients on combo biologic/DMARD regimen had inactive disease Nov 08, 2021
Brepocitinib Shows Promise in Phase II Trial for PsA Oral tyrosine kinase 2/JAK-1 inhibitor improved both joint and skin manifestations Nov 07, 2021
Targeting IL-23 Succeeds in Psoriatic Arthritis Patients had active, longstanding disease and inadequate responses to other agents Nov 07, 2021
Can Abatacept Reverse Early Rheumatoid Arthritis? At-risk patients showed improvements in inflammation -- and also delays in disease onset Nov 06, 2021
TYK2 Inhibition Promising in Psoriatic Arthritis Phase II study found significant benefits for two doses of novel agent Nov 10, 2020
High B-Cell Depletion Succeeds in Lupus Nephritis Obinutuzumab was more effective at depleting B cells than rituximab Nov 08, 2020
COVID Complications Common with Rheumatic Disease Adverse outcomes included acute kidney injury and congestive heart failure Nov 08, 2020
Rinvoq for RA: Benefits Persist Beyond 1 Year Manufacturer's extension study shows no loss of clinical response Nov 06, 2020
ACR: Treat-to-Target Endorsed for Gout Differs from ACP guideline for primary care: "they're wrong" Nov 15, 2019
ACR: Draft OA Guidelines Stress Non-Drug Tx, Leave Opioid Door Open But group comes down hard on stem cells, PRP, electrical therapy; downgrades hyaluronic acid shots Nov 14, 2019
Rheumatoid Arthritis Is No Bar to Cancer Immunotherapy Small study finds flares common with checkpoint inhibitors, but few patients stopped treatment because of them Nov 13, 2019
Reassurance on Live-Virus Shingles Vax With Anti-TNFs Randomized trial indicates fears of infection unfounded Nov 11, 2019
BTK Inhibitor Passes Phase II Test in RA Novel mechanism for a rheumatoid arthritis drug Nov 11, 2019
ACR: Can Tanezumab Be Revived for OA? Low incidence of rapidly progressive OA seen with lower doses Oct 26, 2018
In Psoriatic Arthritis, Doubling Down on IL-17 Bimekizumab targets both IL-17A and F; "astonishing" results in psoriatic arthritis Oct 25, 2018
Treat-to-Target Strategy Cuts Mortality in Gout Patients Study sets serum urate therapeutic level Oct 24, 2018
ACR: IL-12/23 Blocker Offers Long-Term Benefits in SLE Responses were sustained out to 1 year with ustekinumab Oct 24, 2018
Childhood Trauma: Risk Factor for Lupus in Adulthood? Nurses Health Study data show a link Oct 24, 2018
RA Guideline Adherence Spotty, Study Finds Treat-to-target recommendation not followed for half of patients Oct 23, 2018
Recurrent Post-Transplant Lupus Nephritis Declining Single-center study credits improvements in immunosuppression Oct 23, 2018
Is JAK Inhibition the Next Big Thing in PsA? Proof-of-concept study suggests a potential role for oral filgotinib Oct 22, 2018
New JAK1 Agent Beats Humira in Rheumatoid Arthritis Thrombotic events balanced between upadacitinib, adalimumab, and placebo Oct 22, 2018
Selective IL-23 Inhibitor Shines in Mid-Stage PsA Trial Risankizumab broadly effective against joint and skin symptoms Nov 09, 2017
PsA Structural Damage Inhibited with Secukinumab Loading dose appears to improve outcomes, researchers say Nov 09, 2017
Novel Drug Promising for IgG4-Related Disease 8 of 15 patients achieved remission in phase II study Nov 08, 2017
Prospects Good for Ustekinumab Gaining SLE Indication Positive phase II data reported in ACR late-breaker Nov 08, 2017