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ISC

BEST-II Throws Cold Water on Already-Tepid BP Lowering After Stroke Thrombectomy

Trial did not show definite harm, but benefit is unlikely

Lessons From Flint, Mich. on Stroke Preparedness and Lytic Uptake

Racial disparities narrowed as a result of hospital and community intervention

Does All Afib Detected After Stroke Really Have to Trigger Oral Anticoagulation?

Stroke neurologists debate skipping secondary prevention anticoagulants for some

Suboptimal Sleep Duration Linked to Poor Brain Health

Middle-age patients with worse sleep saw increased white matter hyperintensities on MRI

Tenecteplase on Par With Alteplase, Randomized Trial Affirms

Data from China strengthen the evidence base for off-label use

Familiar Drugs Get a Foot in the Door for Small Vessel Stroke Treatment

Combined isosorbide mononitrate and cilostazol feasible, well tolerated in these patients

DAPT Underused for Minor Stroke, TIA

Registry suggests undertreatment, particularly of women and healthier individuals

Stroke Neuroprotection Drug Passes Early-Phase Hurdle

Infusion before mechanical thrombectomy reduced important outcomes in small phase I/II trial

Does the Environment Override Genes for People at Risk of Stroke?

Large study detects interaction between genetic susceptibility and neighborhood deprivation

Cardiac Monitoring Continues to Flag Unsuspected Afib in Broader Population

STROKE AF studied a group not typically considered for Afib detection and management

Certification Status Makes a Difference for Stroke Centers

Lower-level hospitals performing a "surprising" number of thrombectomies

Evidence for Stroke Thrombectomy in Kids 'as Good as It Gets'

Expansion of EVT bolstered by population-based study from Australia

Stroke Clot Composition Linked to Functional Outcomes, Death

Study hints at personalized treatment potential

DOACs Working Out for CVT Strokes So Far

Findings of ACTION-CVT provide some reassurance

Lytic Post-Thrombectomy Improved Stroke Outcomes

But a number of problems with clinical trial may require a redo

Can Tenecteplase Help Late-Presenting Strokes?

Early phase data from China suggestive of benefit

Tirofiban: A Questionable Addition to Stroke Thrombectomy

Glycoprotein IIb/IIIa receptor inhibitor does show promise for one subgroup in randomized trial

Intensive Dental Care on Shaky Footing for Cardiovascular Prevention

Stroke survivors fared similarly with regular treatment for gum disease

Emergent Stroke Care Within Reach for Nearly All in U.S.

Next question is staffing at those centers

Thrombectomy Helps Large Core Strokes

Randomized trial shows "surprising" magnitude of benefit on par with that in smaller infarcts

Positive Data Salvaged for Thrombectomy on Basilar Strokes

BEST, BASICS trials not wholly negative, group finds

COVID Strokes: Rates, Types, Disparities

The latest stroke data from the pandemic illuminates patterns

Stroke Thrombectomy: 6-Hour Threshold Not So Relevant?

Pooled trial analysis supports move to imaging-based criteria

Stroke Care: Some Progress on Racial Disparities

But substantial gaps remain

Adjustable Stent Retriever Passes Muster

Novel device offers better grip on clots in LVO strokes

Novel Vasoregulator Explored for Acute Ischemic Strokes

Early results may signal benefit for those not treated with thrombectomy

Loop Recorder Proves Mettle in Broader Stroke Population

STROKE AF trial supports use outside of cryptogenic stroke category

Don't Ditch the tPA in Stroke Thrombectomy Yet

Direct endovascular therapy dealt a blow in MR CLEAN-NO IV

Time to Stop Routine Anesthesia for Stroke Thrombectomy?

Neurologists debate pandemic-related guidelines

Immediate Angiography Feasible for Large Vessel Stroke Patients

Not stopping patients in the ED improved hospital workflow and patient outcomes

Multi-City Study Bolsters Case for Mobile Stroke Units

But reimbursement woes, balkanized EMS agencies block path to broader use

Off-Label Alternative to Alteplase Superior for Routine Stroke Thrombolysis?

U.S. center reports favorable experience with arguably better lytic drug

Lytic Still Needed for Endovascular Stroke Tx

First RCT not definitive but misses non-inferiority

Mobile Stroke Unit Availability Improves Stroke Clinical Outcomes

Berlin's experience with the world's first units shows the payoff

Hopes for Novel Stroke Drug Dashed in Trial

But ESCAPE-NA1 signals neuroprotectant might work if given without thrombolytic

Out of the Basement: Early Results Promising for Portable MRI

Feasibility study indicates no interference in ICU, no metal issues

Game-Based Stroke Rehab From Home On Par with Clinic

Arm motor function recovery was noninferior in randomized trial

Lytics Help Imaging-Selected Patients Beyond 4.5-Hour Window

EXTEND trial shows less disability after use in 4.5-to-9-hour window

Andexanet Holds Strong as Antidote to Apixaban, Rivaroxaban

Reversal agent for factor Xa inhibitors soon to be subject to a randomized trial

Benefit of Endovascular Therapy Dwindles With Large-Core Strokes

But is thrombectomy still better than medical management alone for these cases?

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