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Diabetes

News, opinions and meeting coverage in nephrology.

The letters AACE over a pic of the Los Angeles convention center.

Improvements in Excess Cortisol Activity With Relacorilant

Phase II study of selective glucocorticoid receptor modulator found dose-dependent effect

An illustration of an obese male losing weight over a box of Metformin.

Weight Loss With Metformin Maintained at 15 Years

But magnitude was modest versus lifestyle intervention

Two bottles of the medication Jardiance.

Jardiance May Help Heart by Shifting Its Fuel

Animal study supports mechanism for glucose-independent effects

A bottle of inulin over a medical illustration of the gut microbiome.

Inulin Boosts Insulin Sensitivity in Overweight Adults

Benefits appear related to changes in gut propionate and amino acids

Close up of a woman itching her arm.

Itchy Skin Threatens CKD Patients' Quality of Life

More severe cases seen in those with higher stages of chronic kidney disease

鈥淎CP鈥� over photo of the Pennsylvania Convention Center.

Patient Says Allergic to Penicillin? Maybe, Maybe Not

Often these cases can be safely re-challenged

Older Adults Still Struggle With Hypoglycemia

Endocrine Society issued new diabetes clinical practice guidelines for older adults

Oral Semaglutide Tops Sitagliptin for Cutting HbA1c, Weight in T2D

Positive results from PIONEER 3 trial in diabetic patients who aren't responding to metformin with or without sulfonylurea

Is a Widely Used T2D Test Off the Mark?

Presence of diabetes, normal glucose tolerance defined only by HbA1c not reliable, study claims

Intensive Early Glucose Control No Help for Stroke Recovery

SHINE trial yields similar functional outcomes but higher hypoglycemia risk

Body Weight and Heart Disease; New Osphena Indication; Tofu and Appetite

News and commentary from the endocrinology world

Comorbidities Common in Older 'Frequent Fliers' in the ED

Diabetes topped the list; pain-related diagnosis and injury were other factors

Will Biomarkers Eventually Replace Physicians?

Milton Packer imagines the end of nonprocedural medicine as we know it

The Most Wonderful Mistake the FDA Ever Made

Milton Packer explains how an FDA error enlightened the practice of medicine

Ultrasound for Diabetes Screening?

Brightness of deltoid muscle can give clues to diabetes status

Omega-3 and Vitamin D; Vein Grafts and CABG: It's PodMed Double T!

This week's topics include benefits of CABG, vein harvesting, new exercise guidelines, and omega-3 and vitamin D supplementation

Metabolic Surgery Prevails for Mortality, CV-Risk Reduction in T2D

Macrovascular complications, CV mortality reduced more with surgery than medical therapy alone

Bariatric Surgery Outcomes Vary According to Obesity Subtype

Researchers identified four separate classes of obesity

AHA: CABG Still Better for Multivessel Disease in Diabetes

FREEDOM trial extension suggests lower long-term mortality vs stents

Heart Benefit with Dulaglutide; New Hot Flash Therapy; Diabetes Risks in Women

News and commentary from the endocrinology world

AHA: Late Meals Linked to HTN, Prediabetes

Risks seen in study of Hispanic and Latino Americans

SGLT-2 for Stage 3 CKD; Opioids for CKD; Kidney Transplant Discard & Disabilities

Roundup of more top abstracts from Kidney Week 2018

Kidney Outcomes Mixed Bag with Intensive Metabolic Care

Tight glucose control reduced, while intensive BP goals raised

Linagliptin CV Safety; Insulin Storage; Renal Outcomes

Round-up of more top research from the 2018 EASD meeting

Dual GIP/GLP-1 Agonist Succeeds in T2D Trial

Novel diabetes treatment improved HbA1c, aided in weight loss

Death Risk Elevated in Dementia Patients with Hypoglycemia

Target hypoglycemic episodes instead of HbA1c, researchers urge

Deaths from Non-Obesity-Related Cancers Higher in T2D

Even in some obesity-related malignancies, high BMI was inversely tied to cancer death

Heart Benefit Seen with GLP-1 RA Albiglutide

Significant reduction in myocardial infarctions; will drug be brought back to market?

Risks Seen for Tight BP Target in Diabetics?

Intensive treatment tied to serum creatinine increase, eGFR decrease

Robots and Surgery; Alcohol and Death: It's PodMed Double T!

This week's topics include Parkinson's disease and metabolic syndrome, lorcaserin and heart problems, the global burden of alcohol related disease, and robotic surgery costs.

Primary Prevention Headlines at ESC

Will aspirin, fish oil pan out in big trials?

'Test and Treat' Programs Reduce HIV Infections

Multi-disease attack shows benefits across the board

Cancer Risk With Diabetes Higher in Women than Men

Authors recommend "sex-specific approach" to prevention and treatment

Verapamil Success for T1D; Bariatric Surgery Wait; Self-Monitoring Without Insulin?

News and commentary from the endocrinology world

SGLT-2 Inhibitors Tied to Lower All-Cause Mortality Risk

Head-to-head comparison with DPP-4 inhibitors also showed heart protection

'Artificial Pancreas' System Boosts In-Hospital T2D Control

Less time out of range, no increase in insulin or lows with fully-automated system

Early T2D Treatment in Youth Disappoints

Metformin, insulin didn't stop deterioration of beta-cells in adolescents with impaired glucose

Intensive Treatment Doesn't Cost More

Therapy aimed at treating all organ targets extends life

Sotagliflozin Tx Tied to HbA1c Reductions in T1D

But instances of diabetic ketoacidosis are a concern, expert says

Basal Insulin Doesn't Cut Hypoglycemia Risk Vs NPH in T2D

Similar hypoglycemia-related emergency department and hospital admissions

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