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Dementia

News, opinions and meeting coverage in neurology.

Feared ARNI Effect on Cognition Hasn't Come to Fruition

Neurocognitive protection by sacubitril/valsartan suggested instead by observational study

A computer rendering of a heart cross section with implanted left ventricular assist device

Some Reassurance on Cognition in People With Older LVADs

Will newer devices look even better for neurological outcomes?

A technician prepares blood samples for mass spectrometry

Blood Test Discerns Alzheimer's From Other Dementia With High Accuracy

Plasma p-tau moves another step closer to clinical use

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Driving Patterns Pinpoint Early Alzheimer's Disease

Subtle shifts in on-road behavior suggest GPS-based biomarkers may have merit

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

COVID-19: Persistent Cognitive Effects, Uptick in Alzheimer's Biomarkers

Findings link cognitive impairment and long-lasting anosmia

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Aducanumab: What to Know If You Prescribe

Recommendations may change when trial data are published

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Better Air, Better Brains

Reducing air pollution tied to lower dementia risk, slower cognitive decline

Illustration of a brain shaped maze.

Drug Overdoses Spike; Shock Therapy Effective; Psychiatrist Charged for 'Pill-Mill'

News and commentary from the psychiatry world

A stressed looking senior woman next to a bottle of Nuplazid (pimavanserin) capsules.

Staying on Pimavanserin Cut Dementia-Related Psychosis Relapse

However, late-stage trial couldn't separate efficacy in dementia subtypes

A senior woman talks on her smartphone at home.

Phone Calls Spot Early Alzheimer's

Predictive model identified vocal features of dementia patients from everyday speech

A computer rendering of the release of cytokines.

Two Inflammatory Proteins Linked With Slower Cognitive Decline

Surprise finding ties plasma cytokine levels with Alzheimer's biomarkers and cognition

SLEEP over a conceptual image of dreaming: a woman in a bed floating in the clouds with birds.

Sleep Disorders Tied to Dementia in Patients With TBI

Study evaluates outcomes by sex, independently of other dementia risks

SLEEP over a conceptual image of dreaming: a woman in a bed floating in the clouds with birds.

Trouble Falling Asleep Predicts Later Cognitive Impairment

Depression and vascular disease may play roles

A photo collage of a wall clock and a portrait of a senior man staring into space and disintegrating into particles.

Cognitive Clock Predicts Brain Health

Brain age forecasts outcomes better than chronological age

A computer rendering of phosphorylation of tau proteins

Simple Tool Predicts Individual Alzheimer's Risk

Blood and quick cognitive tests boost accuracy to 90%

A young female nurse gives medication to an elderly woman laying in bed

Blood Thinners Continue at End of Life, Despite Risks

No clear guideline for stopping anticoagulants in patients with advanced dementia

APA over an illustration of a red hand pulling a tangled thread from a woman鈥檚 head

Dissolving Film Quells Agitation in Schizophrenia, Bipolar Disorder

Improvements seen in 30 minutes or less with investigational oral agent

A mature businessman rests his chin on his handcuffed hands

Four Sentenced in Mental Health Center Scam

Heads of a Houston healthcare chain will go to prison for kickbacks, mental healthcare fraud

A mature man sitting at his desk checks his blood sugar with a glucose meter

Diabetes, Dementia, and Age: What's the Link?

Age of diabetes onset, as well as cardiovascular comorbidities, play large role in dementia risk

A mother sits next to her sad looking young daughter on the couch

In Depression, the Apple Doesn't Fall Far From the Tree

Study shows kids have increased depression risk with family history

AAN over a computer rendering of synapses signaling

Blood-Based Markers Tied to Brain Cell and Memory Loss

Another step closer to clinical utility for tracking neurodegeneration

A computer rendering of the human heart showing a lack of blood flow

CaMKII Inhibitor Disappoints in Post-MI Cardioprotection

First agent of its kind to test the waters in heart disease

A young man lays on the couch wincing and pinching the bridge of his nose which is highlighted in yellow

Chronic Sinusitis May Affect Neural Function

Study supports inflammation as link between sinonasal inflammation, cognitive deficits

Illustration of a brain shaped maze.

New ADHD Drug OK'd; Pimavanserin Rejected for Dementia Psychosis

News and commentary from the psychiatry world

Ophthalmoscopy of glaucoma

Eyes Offer Window Into Cognitive Impairment

Glaucoma study provides more evidence of common neurodegenerative pathway

A conceptual image of a senior Asian man with his hand on his forehead and his mind disintegrating into particles

Dementia Diagnoses Lag in Ethnic and Racial Groups

Asian, Hispanic, Black people diagnosed at later stages than white people

A man wearing a party hat sits alone at a table in front of a birthday cake

Middle-Age Loneliness Linked to Alzheimer's Disease

Relationship varied, depending on whether loneliness persisted

Brain scan images with NeuroBreak in the center.

Bacon and Dementia Risk; Zinc Fingers and Tau; Older Adults Light Up

News and commentary from the world of neurology and neuroscience

A cutaway of a normal brain next to a cutaway of a brain with CTE

Criteria Proposed to Diagnose Clinical Syndrome Tied to CTE

Traumatic encephalopathy syndrome definition applies to research, not clinical care

Four portraits of an anguished man blended together

High Prevalence of Early-Onset Dementia in Schizophrenia Patients

More than a quarter had a dementia diagnosis by age 66

Illustration of a brain shaped maze.

New ADHD Stimulant OK'd; Anticonvulsant for Depression?

News and commentary from the psychiatry world

A senior woman in front of her open medicine cabinet using a pill organizer

Dementia Patients Often Have Dangerous Mix of Drugs at Home

Combinations increase risk of falls, respiratory suppression, cognitive impairment

Brain scan images with NeuroBreak in the center.

Sleep-Dementia Link; Neanderthal Mini-Brains; MS Tx and COVID Vax

News and commentary from the world of neurology and neuroscience

An MRI of the brain showing perivascular spaces

Dementia Tied to Large Perivascular Spaces

Enlarged spaces around cerebral small blood vessels linked to cognitive decline over time

A smiling woman who has just turned 100 points at her head

High Cognitive Performance at Age 100

Some centenarians show resilience to cognitive decline, despite brain pathology

An illustration of a person's thoughts and memories connected to their brain

Primary Progressive Aphasia in Alzheimer's Doesn't Foretell Memory Loss

No memory decline over more than 2 years in small study, though speech deficits grew

A male nurse holds a stethoscope to the chest of a Black female patient, both are wearing protective facemasks

Altered Mental State Tied to COVID-19 Mortality

In-hospital deaths higher, even when pulmonary problems were not severe

The illustration used in the Cookie Theft Task

Language Predicts Alzheimer's Onset

AI model uses linguistic dysfunction to spot future dementia

The chemical structure of equol over a photo of soybeans and soy-based foods

Soy Metabolite Tied to Dementia Risk Factor

Equol production linked to lower white matter lesion levels

A box of Metformin tablets

More Evidence for Cognitive Benefits With Metformin in T2D

Prospective study followed more than 1,000 older patients for 6 years

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