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General Neurology

News, opinions and meeting coverage in neurology.

A computer rendering of nerve cells affected by Lewy bodies

Can a GLP-1 Agonist Improve Parkinson's Symptoms?

A version of exenatide failed a phase II trial, but hinted at benefits in patients under 60

Neuro Break over a computer rendering of neurons.

Dementia and Estrogen; Case Report on Fatality After Lecanemab; MRI-Based Brain Age

News and commentary from the world of neurology and neuroscience

An computer rendering of the crossection of the spinal cord

Spinal Cord Stimulation Questioned for Chronic Pain

Independent studies suggested no benefit, but industry-funded critics cast doubt on the findings

A photo of a mother feeding her baby mashed avocado.

Keto Diet on Par With Further Medication for Infants With Drug-Resistant Epilepsy

Diet may be considered a treatment option for some infants who continue to have seizures

A photo of a mature man lying in bed awake with his arm across his forehead.

Dementia-Sleep Link Has a New Twist

Research unravels relationship between irregular sleep and poor brain health

FDA approved oral eflornithine (Iwilfin) over a computer rendering of a tumor of the adrenal gland.

FDA OKs Maintenance Option for High-Risk Neuroblastoma

Eflornithine approved to reduce relapse risk in both kids and adults

Neuro Break over a computer rendering of neurons.

Twins and Dementia; CRISPR and Alzheimer's; BTK Inhibitor Fails in MS Trials

News and commentary from the world of neurology and neuroscience

An MRI image of the brain of a person with Creutzfeldt-Jakob disease

Prion Disease Rising in the U.S.

Incidence of Creutzfeldt-Jakob disease increased, especially among women

A computer rendering of robot hands typing on a keyboard.

ChatGPT Takes on the Neuro Boards

The AI model used very confident language, even when it was wrong

A photo of a woman lying in bed with her arm across her eyes.

This Many U.S. Adults Have Chronic Fatigue Syndrome

In survey, 1.3% report having an ME/CFS diagnosis

A computer rendering of the dorsal striatum and lateral ventricles in the brain of a person with Huntington鈥檚 disease

Antisense Drug Trial Provides Key Insights About Huntington's Disease

Lessons learned from investigational tominersen

A computer rendering of the organs of human body as seen through transparent skin.

Blood Test May Be Able to Tell Which Organs Have Accelerated Aging

This may enable treatment of people before they get sick, researcher says

A photo of a test tube of blood labeled: Alzheimer鈥檚 disease, laying on a stainless tray.

Alzheimer's Blood Test Predicts Who Might Benefit Most From Anti-Amyloid Drugs

Novel two-cutoff approach may reduce need for confirmatory PET scans

Neuro Break over a computer rendering of neurons.

Personality Predictors of Dementia; Parkinson's Blood Test; Klotho in Alzheimer's

News and commentary from the world of neurology and neuroscience

A photo of x-rays of implanted electrodes in a patient鈥檚 brain.

Deep Brain Stimulation Revives Cognitive Function After Traumatic Brain Injury

Pilot study shows promise in people with chronic cognitive deficits

A photo of an unhappy looking woman under a blanket on a couch.

Rare Syndrome After COVID Vaccines Described

"Long vax" events often include neurologic symptoms

A photo of a young woman driving a mobility scooter in a park.

Progression Independent of Relapse Activity in Pediatric-Onset MS

Early treatment with disease-modifying therapy may offer some protection

A computer rendering of numerous eosinophils in the blood.

FDA Warns of Rare Life-Threatening Reaction to Anti-Seizure Drugs

Prescribing information changed for levetiracetam, clobazam

A photo of a gavel and a statue of lady justice in front of the New Jersey state flag.

Medical Staff Credentialing Case Heads to New Jersey Supreme Court

Neurosurgery practice claims hospital skipped due process to orchestrate its ouster

Neuro Break over a computer rendering of neurons.

Alzheimer's Tied to Military Service; Long COVID Sleepiness; NurOwn Tries Again

News and commentary from the world of neurology and neuroscience

RSNA over a photo of McCormick Place South in Chicago, Illinois.

COVID Tied to Changes in Brain Microstructure

Alterations seen in both long COVID patients and those who recovered from infection

A photo of a senior man sitting over a puzzle and talking on a smartphone.

Cognitive Scores Improve With Personal Coaching

Trial shows better outcomes for people at high dementia risk

A computer rendering of amyloid plaques clumped between nerve cells.

Alzheimer's Drug Trials Should Report Effect Sizes, Researchers Say

How effective are anti-amyloid treatments?

A photo of a pregnant woman sitting on a couch holding a glass of water and a pill.

Adaptive Functioning Not Affected in Children of Women With Epilepsy

But increasing medication exposure in third trimester tied to a decline in function

Neuro Break over a computer rendering of neurons.

Alzheimer's Vaccines Are Back; Streamlining Prior Authorization; Rare APOE Variant

News and commentary from the world of neurology and neuroscience

A photo of a blue rubber gloved hand holding a test tube labeled: TOTAL PROTEIN TEST

Proteins Predict Signs of Alzheimer's Disease

Subclinical health indicators tied to markers of Alzheimer's and neurodegeneration

A photo of an infant receiving oral medication via a syringe.

Giving DHA to Preemies Doesn't Improve Behavioral Outcomes Later On

At age 5, kids born at

A photo of a female physician examining the eye of a premature infant.

Impaired Neurodevelopment in Preemies Screened for Retinopathy: Nature or Nurture?

Study highlights role of insurance type/socioeconomic factors in neurodevelopmental outcomes

A computer rendering of the brain with the hippocampus highlighted.

Hippocampal Atrophy Might Not Signal Alzheimer's Disease

Measuring tau and hippocampus in addition to amyloid may improve Alzheimer's diagnosis

A computer rendering of amyloid beta peptide.

Gantenerumab Failed to Slow Cognitive Decline in Early Alzheimer's

Amyloid plaque levels went down, but not enough for clinical benefit

ACAAI over a photo of Anaheim Convention Center in Anaheim, California.

Added Leukotriene Receptor Antagonists Show Benefits in Chronic Urticaria

Off-label use along with antihistamines improved activity, itch, and wheal count scores

A computer rendered cross section of the spine.

Long COVID Immune Profiles Appear Largely Normal

Brain inflammation may not be a cause of long COVID cognitive problems

Neuro Break over a computer rendering of neurons.

Handheld Device Detects Alzheimer's Biomarkers; Long COVID Smell Loss; MS Fatigue

News and commentary from the world of neurology and neuroscience

A photo of a sad looking senior man sitting in a wheelchair outdoors.

Parkinson's Patients Have Higher Suicide Risk

About 1 in 5 harbored suicidal thoughts

A photo of foods associated with the MIND diet.

MIND Diet in Midlife Tied to Higher Subcortical Brain Region Volumes

Relationships appear to hold regardless of Alzheimer's genes

A photo of vials of botulinum toxin and a syringe sitting in a stainless tray.

Botulinum Toxin Lessens Head Tremor Severity

Improvements lasted up to 18 weeks, trial shows

A Parkinson鈥檚 patient walks with spinal stimulation. Credit: Courtine, et al.

Advanced Parkinson's Patient Regains Ability to Walk Confidently

Spinal implant nearly eliminates freezing of gait

Neuro Break over a computer rendering of neurons.

Biological Age Predicts Dementia; APOE4 and Tau Patterns; AI and MS Brain Changes

News and commentary from the world of neurology and neuroscience

A computer rendering of the demyelination of a neuron.

Blood Test Detects MS Disability Worsening a Year Before It Occurs

Neurofilament light is elevated before worsening, both with and without relapses

Botulinum Toxin Injection May Be an Option for Excess Saliva in Patients With ALS

Small VA-based study saw promising short-term results with no adverse events

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