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Migraines

News, opinions and meeting coverage in neurology.

Oral Meds Relieve Acute Migraine Attacks

Rimegepant and ubrogepant lessen headache pain and bothersome symptoms

Migraine Patterns Often Change During Menopause

Falling estrogen levels may worsen headaches

Patients Often Mistake Migraine 'Triggers'

Tracking app data show little association for chocolate, nitrates, MSG

Galcanezumab Offers Help for Cluster Headache and Migraine

CGRP blocker reduced frequency of both types of headache more than placebo

Lasmiditan Provides Rapid Migraine Relief

First-in-class drug promises efficacy without cardiovascular side effects

Comorbidities Can Help Predict Migraine Progression

Migraineurs fall into eight natural subgroups based on coexisting health problems

Migraines Can Put Strain on Family Ties

Studies show chronic migraines impact spousal, parent-child relationships

AHS Conference Surveys Changing Migraine Landscape

CGRP inhibitors and a whole lot more

Eptinezumab Effective in Chronic Migraine

Intravenous CGRP blocker shows rapid treatment effect

Oral CGRP Inhibitor Helps Relieve Migraine Attack

About 20% report being pain-free within 2 hours

AAN 2018: Rare Disease Breakthroughs and Novel Approaches

Noteworthy presentations at American Academy of Neurology meeting

Erenumab Reduces Migraine in Hard-to-Treat Patients

But questions about long-term risks remain unanswered

Pearls from: Matthew Robbins, MD

Managing headache disorders during pregnancy

Novel Biologic Works for Episodic Migraine Prevention

But effect size small with erenumab, and questions about vascular risk remain

Astronauts' Blurred Vision Tied to CSF Volume Shifts

Brain structure seems unaffected by space flight

Make the Diagnosis: Strange Syncope

Case Findings: A 56-year-old male presents with multiple episodes of syncope. One episode occurred while driving his motorcycle, causing him to sustain multiple nonsurgical cervical spine fractures. An MRI of the brain was obtained. What is your diagnosis?

AHA: Study Finds Celebrex Safe for Heart

But naproxen not as heart safe as believed

Human Birth Defects Seen With Pregabalin

Time for a pregnancy category change?

Botulinum Toxin Guidelines Overhauled

Strong evidence supports specific formulations in spasticity, chronic migraine

TCT: PFO No Panacea for Migraine

WASHINGTON -- Percutaneous patent foramen ovale (PFO) closure did not significantly reduce the number of monthly migraine days compared with medical treatment, researchers reported here.

Now What? DEA Tosses Tramadol in Schedule IV

The Drug Enforcement Administration (DEA) scheduled tramadol as a Schedule IV substance -- whats the big fuss about tramadol that led to this decision by the DEA?

FDA Approves Headband Device for Migraine

A headband delivering electrical nerve stimulation can prevent onset of migraine headaches and can be marketed for that purpose in the U.S., the FDA said Tuesday.

Common Cause for Bruxism, Restless Legs, Migraine?

NEW ORLEANS -- About half of patients with restless legs syndrome (RLS) seen in a single neurology practice also qualified for diagnoses of bruxism and migraine, suggesting a possible common cause for these disorders, a researcher said here.

Triptans Go-To Migraine Drugs Even in Pregnancy

The triptans, most experts agree, are the go-to drugs for frequent or serious migraines in pregnancy.

Migraine Drug May Set Stage for Kidney Stones

ORLANDO - Patients who take topiramate (Topamax) therapy for treatment of migraine appear to deplete citrate in the urine, creating an environment for kidney stones, researchers reported here.

NuPathe's Patch for Migraine Wins FDA Approval

WASHINGTON -- Adults with migraine will soon have a new treatment option -- Zecuity, a transdermal, battery-powered sumatriptan patch.

'Visual Snow' Called Real, Not Drug Related

NEW ORLEANS -- A mysterious and troubling phenomenon called "visual snow" is a distinct syndrome that does not appear to stem from illicit drug use, nor is it a migraine aura, a researcher said here.

Doctors Say 45 Common Tests 'Overused'

Nine specialty groups have listed tests and treatments that are frequently overused, such as antibiotics for sinus attacks and CT scans for low back pain, in the first phase of a long-term project.

Follow the Money: Pain, Policy, and Profit

When the Federation of State Medical Boards decided it needed to put a model guideline for opioid use into a book, it reached out and touched the makers of opioid drugs to make it happen.

Muscle Massage Rubs Out Inflammation

Heavily stressed muscles responded to massage therapy with a variety of biologic changes associated with reduced inflammation, analysis of tissue specimens showed.

Acetaminophen OD More Deadly if Taken in Stages

Acetaminophen overdoses were more likely to be fatal if patients consumed a series of high doses spread over the course of a day rather than downing, say, a bottle of pills at one time, outcomes among patients admitted to a specialized liver center showed.

FDA Warns on Mixing Antidepressants with Migraine Drugs

ROCKVILLE, Md. -- Mixing common migraine drugs such as Imitrex (sumatriptan) with antidepressants like Prozac (fluoxetine) or Cymbalta (duloxetine) can trigger a life-threatening condition called serotonin-syndrome, the FDA has warned.

Drugs That Lower Blood Pressure Also Prevent Headaches

LONDON - Four classes of drugs that lower blood pressure also prevent headaches, say researchers here who analyzed data from 94 randomized, placebo-controlled trials.