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Sleep Disorders

News, opinions and meeting coverage in neurology.

Quinine for Leg Cramps Tied to Increased Death Risk

Adults under age 50 had threefold greater mortality risk

Daytime Sleepiness, Brain Pathology: A 2-Way Street?

Amyloid buildup may be both effect and cause of sleep-wake abnormalities in elderly

Men with Children Sleep Fine; Women Not So Much

Men not bothered by their own snoring, either

Travel Direction Tied to Baseball Teams' Performance

Lower winning percentage on eastbound road trips

ESC: CPAP Flops for Secondary CV Prevention

No impact on coronary, stroke risks from sleep apnea tx in SAVE trial

Telemedicine May Be Boon for Treating Sleep Disorders

Reimbursement uncertainty remains roadblock to wide adoption

Does That Surly Teen Just Need More Sleep?

Nightly sleep fluctuations predicted next-day mood

Gamers Lose Sleep to Keep Playing

Survey findings suggest video gaming is addictive behavior

Late Sleepers Have Worse Diets Than Early Risers

But sleeping late wasn't linked to higher BMI

Snoring Tied to Cognitive Deficits in Young Kids

Highest risk seen in children with severe obstructive sleep apnea

Excessive Sleepiness Lingers in TBI Patients

18 months later, TBI patients slept an hour more each night than healthy controls

Patient Registries See Promise and Challenges Ahead

Physician-driven registries adapt to a changing health system

PD Patients Report Better Sleep With Rotigotine Tx

Patch form of dopamine agonist also lowered nighttime activity

Iron Reduces Parasomnias in Children With Restless Legs

Most with restless legs syndrome and night terrors do well with ferritin supplements

Persistent Sleep Trouble Common in Kids With Brain Injuries

TBI leaves children struggling for months with daytime sleepiness and problems sleeping at night

Sleep Apnea Correlates With Injury on the Job

Accidents while working occurred twice as frequently when sleep apnea was involved

'Sleeping In' Doesn't Make Up for Lost Sleep in Teens

Sleep deprivation may affect work in schools and driving

FDA Advisers Unimpressed by Nocdurna

Another setback for nocturia indication

Sexsomnia: A Case Study of a New DSM-5 Diagnosis

Initiating sex while asleep is not only a drug side effect.

Excerpt From 'Being Mortal ... '

Ivan Ilyich isn't as foreign to today's medicine as we imagine.

'Sleep Drunkenness' Common, But Rarely Unexplained

So-called confusional arousals were reported in the past year by some 15% of respondents in a population-based survey, with nearly all episodes associated with mental disorders or drugs with known sleep effects.

FDA Slashes Starting Dose for Lunesta

SILVER SPRING, Md. -- Patients starting on the sleep drug eszopiclone (Lunesta) should take no more than 1 mg at bedtime -- one-third the current label-recommended dose -- because of the risk of next-day impairment, the FDA said Thursday.

Murder: Another Ambien Side Effect?

NEW YORK CITY -- Forensic psychiatrists are facing new challenges with murders committed by people under the influence of the sleep drug zolpidem (Ambien) -- not least to persuade the criminal justice system to take their conclusions seriously.

APA Meeting Highlights Mental Health Biology

NEW YORK CITY -- The biological basis for normal and abnormal mental function is emerging as a dominant theme in psychiatry research, and the American Psychiatric Association annual meeting that starts here Saturday won't be an exception.

Forget Glucometers, Use Voodoo Dolls Instead: That's Improbable!

A weekly report from our friends at Improbable Research.

Lyrica Edges Mirapex for Restless Legs

Patients with restless legs syndrome treated with pregabalin (Lyrica) had as much symptom improvement as those receiving pramipexole (Mirapex) in a large year-long trial, with fewer showing "augmentation."

Drug Combo Saves Kids' Tonsils in Mild OSA

The anti-inflammatory asthma drug montelukast (Singulair) plus corticosteroids was an effective initial alternative to surgery for mild obstructive sleep apnea (OSA) in children, a retrospective study showed.

Debate: Who Should Prescribe CPAP?

Should primary care physicians and other nonspecialists be able to prescribe sleep apnea treatment after home testing? Experts debated that issue this month in Chest.

Sleep Problems, Poor Angioplasty Outcomes Linked

Disturbed sleep is common in heart patients following coronary angioplasty and is an independent risk factor for poor cardiac outcomes, researchers reported.

Common Cause for Bruxism, Restless Legs, Migraine?

NEW ORLEANS -- About half of patients with restless legs syndrome (RLS) seen in a single neurology practice also qualified for diagnoses of bruxism and migraine, suggesting a possible common cause for these disorders, a researcher said here.

Xyrem Helps With Nighttime Sleep in Narcolepsy

NEW ORLEANS -- Narcolepsy patients troubled by frequent nighttime awakenings had less sleep disruption when taking sodium oxybate (Xyrem) than modafinil (Provigil) in a randomized trial, a researcher reported here.

APA Leaders Defend New Diagnostic Guide

SAN FRANCISCO -- The fifth edition of the "psychiatrist's bible" was officially released here in all its 947-page glory, with its developers offering a spirited rebuttal to their critics.

Hangover Risk Prompts Ambien Label Changes

New dosing recommendations for products containing zolpidem (Ambien, Ambien CR, Edluar) are now included in their labels, along with warnings of next-day hangover effects, the FDA said Tuesday.

FDA: Booze and Xyrem Are Dangerous Mix

WASHINGTON -- The FDA is warning healthcare professionals that patients taking the muscle weakness and narcolepsy drug sodium oxybate (Xyrem) should not consume alcohol or use central nervous system depressants.

Melatonin Can Help Seniors Get More Sleep

BOSTON -- Over-the-counter melatonin appears to provide a measure of sleep for older individuals who have insomnia, a meta-analysis showed.

Child's Epilepsy Keeps Household Up All Night

Children with epilepsy and their parents reported suffering from sleep problems, researchers found.

DSM-5: What's In, What's Out

PHILADELPHIA -- Reports here provided what may be the last public update on DSM-5, the next edition of American psychiatry's diagnostic guide, before it is formally released in May 2013.

Most DSM-5 Revisions Pass Field Trials

PHILADELPHIA -- Field trials of proposed new diagnostic criteria for many mental disorders showed that, for the most part, they were at least adequately reliable.

Latest Use for Botox: Teeth Grinding

茂禄驴NEW ORLEANS -- Patients who ground their teeth so hard during sleep that they required medical attention achieved significant relief from botulinum toxin shots, researchers said here.

Low-Dose Zolpidem Gets FDA Okay for Wee-Hours Awakening

A new formulation of the insomnia drug zolpidem tartrate (Ambien) has been approved to treat middle-of-the-night awakenings followed by difficulty returning to sleep, the FDA said.

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