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Diabetes

News, opinions and meeting coverage in primary care.

FDA Panel Splits on Expanded Jardiance Indication

Questions raised about key trial

Are Expensive Diabetes Drugs Worth It?

Jardiance and Victoza improve hard outcomes, but at a hefty cost

Mixed Findings on High Birth Weight, CV Risk Factors

Some markers of cardiovascular health better with high birth weight

Jardiance Shows Renal Benefit in EMPA-REG

Diabetes drug linked to slowing of kidney disease progression

Biosimilar Insulin Glargine Matches Up With Lantus in Phase III

Merck's copycat has similar HbA1c effect in trial

Survey: Diabetics Get Little Sympathy at Work

Co-workers give more slack to colleagues with other conditions

More Promising Results for Bionic Pancreas

But studies are short-term and relatively small

What's New in Beta Cell Transplantation

Gene editing, stem cells raise new possibilities

LEADER Trial Leads the Pack at ADA

But meeting in New Orleans will also feature thousands of new papers

Preventing Weight Gain in Special Needs Patients

Understanding risks, finding ways to cope

Canagliflozin Leads to Better A1c Control

Post-hoc analysis also finds lower risk of hypoglycemia

Obesity Guidelines Headline AACE 2016

First such guidelines in 25 year history

Vitamin D: Study Finds Impaired Fertility

Study highlights potential adverse effects of too much vitamin D

Long-Term Statin Use Linked to Complications in T2D Patients

But patients not matched at baseline

Blood Pressure Drop for CKD Patients on Patiromer

Sub-analyses finds those with resistant hypertension see benefits

Fanconi Syndrome Seen With Off-Label Canagliflozin

T1D patient presented 1 week after starting drug

CKD Patients With Diabetes Have Altered Gut Bugs

Presence of certain microbes could boost inflammation

NKF: Kidney Transplant Patients Face Diabetes Risk

Meta-analysis findings may impact clinical management and follow-up

Saxagliptin, Alogliptin Linked to Heart Failure, FDA Warns

Decision comes 1 year after FDA advisory committee vote

Whey Protein Tied to Weight Loss in T2D

Glucose levels also dropped with whey versus other protein-based diets

Why Did Afrezza Flop?

Patients don't hate needles that much, docs suggest

Antidepressant Use Tied to Better Diabetes Control

May reflect improved adherence to doctors' advice

Game-Changers in Cardiology: Jardiance Heart Benefit

A diabetes drug that benefits the heart

FDA Lifts Restriction On Rosiglitazone

Agency sees no need for restrictions after easing them 2 years ago

Early Weight Loss With Saxenda Predicts More

Conversely, initial nonresponse is typically maintained

Weight-Loss Surgery a Safe Option for Mildly Obese With T2D

Patients faced a 4.2% complication rate in 30 days

T1D Patients Face Nearly Double Risk for Dementia

Findings still significant after controlling for vascular risk factors.

GI Events Do Not Explain Weight Loss With Saxenda

No difference in weight loss between patients who had nausea and vomiting with diet drug, and those who didn't.

Three Diabetes Drugs Linked to Ketoacidosis, FDA Warns

FDA targets SGLT2 inhibitors canagliflozin, dapagliflozin, and empagliflozin.

Enzyme Rise May Link GLP-1, Pancreatitis

Levels of lipase and amylase don't increase after meals in patients not taking GLP-1 drugs.

TECOS Top Line: No Increase in CV Risk with DPP-4 Inhibitor

Primary and secondary endpoints met for those on sitagliptin.

Slippery Slope: Diet Drugs No Help for Heart

In another edition of the Slippery Slope series examining use of surrogate endpoints in drug approvals, 麻豆传媒 and the Milwaukee Journal Sentinel find diet drugs are approved without solid evidence of benefits, but with hints of harm.

Prediabetes Patients Have Fewer Gut Bugs

A change for the worse apparent in the intestinal microbiome.

Endo Apps: How to Get Useful Glucose Meter Data

There are several options for downloading and interpreting important data from diabetes patients.

Morning Break: Penis Reduction? Patient Suffering

Health news and commentary from around the Web, gathered by the 麻豆传媒 staff.

Diabetes: Is This Tattoo Worth a 1,000 Needle Pricks?

UCSD researchers report early results on a tattoo to measure blood sugar.

Onglyza OK in Renal Patients

No increase in cardiovascular events seen in renally impaired SAVOR patients.

Gut Hormone May Up Dehydration Risk in T2D

Endogenous glucagon-like peptide-1 appears to inhibit fluid intake.

New Treatments for High Potassium on the Horizon

But ultimate success is far from guaranteed.

Stent Graft Keeps Vascular Access Clear

Should change practice, study leader says.

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