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News, opinions and meeting coverage in primary care.

The packaging and blister pack of Cymbalta

Muddled Picture for Antidepressant as Osteoarthritis Pain Reliever

Trial in primary care setting fails to confirm benefit seen in specialty clinics

An illustration depicting Alzheimer鈥檚 disease with amyloid plaques forming between neurons

Alzheimer's Drugs Race to FDA

After aducanumab, drug companies pivot to use the accelerated approval pathway

A Black woman monitors her continuous glucose monitor via her smartphone.

Wide Racial Gap for Diabetes Tech Use Among Medicare Patients

Insulin pump and CGM use significantly lower among black patients

A computer rendering of electricity crackling in a person鈥檚 head.

Post-Stroke Epilepsy Treatment May Influence Mortality

All-cause death lowest in people taking lamotrigine

A photo of Viagra pills blister pack and packaging.

Can Viagra Prevent Alzheimer's?

Sildenafil shows potential for drug repurposing

An illustration of a heartbeat over a silhouette of a senior woman.

Dementia Tied to Resting Heart Rate

Findings persist even after accounting for cardiovascular disease

A vial of Rituxan (rituximab) and bottle of Imbruvica (ibrutinib) capsules over a microscopy of mantle cell lymphoma.

Chemo-Free Regimen Highly Active in Older Mantle Cell Lymphoma Patients

Overall response rate of 96% with ibrutinib-rituximab, but cardiotoxicity a possible issue

A white rubber gloved hand injects platelet-rich plasma into a person鈥檚 knee

Another Trial, Another PRP Flop in Osteoarthritis

Fails to outperform saline in randomized trial

A computer rendering of bone affected by osteoporosis.

Bisphosphonate Therapy and Fracture Prevention: How Long Does It Take?

Meta-analysis determined minimum treatment time needed to see gains

The vial and packaging of Aduhelm (aducanumab) over a close up of a man鈥檚 hand with IV attached.

Let Ethics Guide Aducanumab Prescribing, AAN Says

Don't rely on FDA approval alone to make best choices for Alzheimer's patients

AAO over a photo of the Ernest N. Morial Convention Center in New Orleans, LA.

Microstent for Cataract Surgery Reduced Need for Glaucoma Meds

Device lowers eye pressure by promoting fluid flow through Schlemm's canal

AASLD over a computer rendering of the structure of the liver.

Need for Liver Transplants Rising Sharply in Seniors

Post-transplant mortality still higher versus younger patients, but improving over time

A medical illustration of a dopaminergic neuron in parkinson鈥檚 disease.

Early Parkinson's Treatment: AAN Issues New Guidelines

Levodopa usually is best first therapy for motor symptoms, neurology group says

An MRI image of a brain with Alzheimer鈥檚 disease.

One Aducanumab Patient, Six Brain Edema Episodes

"Uniquely complicated course" for patient treated with new Alzheimer's drug

A close up of a woman鈥檚 hands lifting a vial of Shingrix from a box.

Guillain-Barre Risk Up Slightly After Shingrix

Findings support FDA warning for recombinant zoster vaccine

A computer rendering of ankle osteoarthritis

No Love for PRP in Ankle Osteoarthritis Trial

Dutch researchers throw cold water on popular therapy

CHEST over a computer rendering of the anatomy of the lungs.

Ho-Hum Oral Presentations on COPD Turn Into Fascinating Roundtable

Here's why online meetings can be great

A senior man checks his blood sugar with a glucometer

No Benefit to Intensifying Diabetes Meds at Hospital Discharge

Older adults discharged with intensified regimen had higher risk of severe hypoglycemia

Three boxes of Ivermectin tablets from various manufacturers.

Ivermectin for COVID-19 Linked to Severe Toxicity in Small Study

Confusion, ataxia, seizures, hypotension -- and for some, ICU admission

Rolls of clear plastic film in a food packaging plant.

Exposure to Certain Phthalates Tied to All-Cause, CV-Related Death

Common chemicals in shampoo, cosmetics also linked with billions of dollars in lost productivity

ASBMR over a computer rendering of a human skeleton

Forteo Injection May Soon Face Competition From a Pill

Same peptide formulated for oral administration passes phase II test

A senior man sleeps in a hospital bed.

Can the Death Rattle Be Silenced?

Randomized trial says yes, but results may be challenging to put into practice

ASBMR over a computer rendering of a human skeleton

Supplements to Prevent Bone Breaks? VITAL Says Forget It

Landmark trial throws more cold water on vitamin D, omega-3 pills

HTN over an illustration of a blood pressure monitor and other objects related to hypertension.

Remote BP Monitoring Dips a Toe Into Post-Acute Care

Hypotension emerges as a risk in pilot study

EASD over an illustration of a person's hand and blood glucose monitor and other icons associated with diabetes.

Could a Bisphosphonate Prevent Type 2 Diabetes?

Study finds association between alendronate use and future diabetes risk

A close up of a man's white rubber gloved hand picking up a bullet shell from the floor with tweezers.

Preventing Gun Violence in Patients With Dementia

Gun safety advocate Emmy Betz, MD, MPH, offers advice

ERS over a computer rendering of the respiratory system.

Another Ivermectin Flop; 'Instant' Lung Cancer Decision Tool; Triple COPD Tx & Death

Highlights from the European Respiratory Society virtual meeting

ERS over a computer rendering of the respiratory system.

Targeting Bacteria in COPD Shows Promise

Great potential seen despite mixed results in two new trials

ERS over a computer rendering of the respiratory system.

Feeling Better in COPD: Simple Solution?

No fancy high-tech drug needed, studies suggest

ERS over a computer rendering of the respiratory system.

'Hot Enough for You?' It's No Joke for COPD Patients

Increased risk of exacerbations with hot weather, study finds

ESC over a perspective view of a heartbeat on a vital signs monitor.

Good Results When Giving Flu Shots to MI Survivors Still in the Hospital

Vaccination prior to discharge linked to heart benefit

ESC over a perspective view of a heartbeat on a vital signs monitor.

Lower BP Targets Again Affirmed in Major Trial

STEP trial from China shows major benefits in older population

ESC over a perspective view of a heartbeat on a vital signs monitor.

Mineral Oil Likely Accounts for Some -- But Not All -- of Vascepa's ASCVD Benefit

Danish study fans the flames of REDUCE-IT controversy

ESC over a perspective view of a heartbeat on a vital signs monitor.

Polypills Ready for Prime Time in Large Swaths of People, Researchers Say

Question now is how to implement fixed-dose combo therapy in clinical practice

A bottle of Nuplazid (pimavanserin) capsules over a photo of a senior woman hiding her eyes with her hands.

Parkinson's Drug Tied to Increased Hospitalizations, Death

Mortality risk persisted in people taking pimavanserin

Retinal imaging of nonproliferative diabetic retinopathy

Anti-VEGF Injections Preserved Vision in Severe Diabetic Retinopathy

Aflibercept also reduced vision-threatening complications

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Driving Patterns Pinpoint Early Alzheimer's Disease

Subtle shifts in on-road behavior suggest GPS-based biomarkers may have merit

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

COVID-19: Persistent Cognitive Effects, Uptick in Alzheimer's Biomarkers

Findings link cognitive impairment and long-lasting anosmia

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Aducanumab: What to Know If You Prescribe

Recommendations may change when trial data are published

AAIC over a computer rendering of phosphorylation of tau proteins leading to disintegration of microtubuli in a neuron axon

Better Air, Better Brains

Reducing air pollution tied to lower dementia risk, slower cognitive decline

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