This is one of the few studies to have investigated the manifestation and treatment of thyroid eye disease in Black populations. Compared with White patients, Black patients with thyroid eye disease presented with fewer features on clinical exam. Treatments were similar in both groups, however.
Even long after the active phase of thyroid eye disease has subsided, a multitude of challenging quality-of-life issues may persist.
Asymmetric disease may occur in one-third of patients with thyroid eye disease, with muscle volume expansion possibly contributing to the asymmetry. A standardized definition of asymmetry using more objective parameters is needed to facilitate comparisons among studies.
Investigators retrospectively reviewed medical records of patients with thyroid eye disease to determine the most useful biomarker for extraocular muscle enlargement.
A South Korean study followed patients with thyroid cancer to assess for risk of Graves’ orbitopathy, finding an association with radioactive iodine treatment.
According to a study from Mayo Clinic, pregnancy-associated plasma protein A has a role in the pathogenesis of thyroid eye disease and may be a more selective target for novel therapies modulating insulin-like growth factor activity, the main driver of TED.
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