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Arthritis

News, opinions and meeting coverage in rheumatology.

Bruton's Tyrosine Kinase Marches on as Rheumatology Target

Industry remains interested despite lackluster phase II results with Celgene drug

Injecting Arthritic Knees Carries Sepsis Risk

Study identified four risk factors for sepsis after injections for knee pain.

In RA Patients, 2-Week Methotrexate Holiday Boosts Flu Vax Efficacy

Pragmatic trial shows 15%-20% bump in antibody titers

ACR 2017: Biosimilar Debate, Inflammation in OA, and More

Special lecture will look back at TNF as rheumatology drug target

Helping Kids with Chronic Diseases Move to Adult Care

Program at Wisconsin hospital develops self-management skills

Tofacitinib Shows MRI Benefits in AS

Improvements seen on MRI for both sacroiliac joints and spine

Remission Common in Early SpA With Golimumab

Drug-free remission maintained for more than half after at least 12 months

RA Drug Active in Psoriatic Arthritis

Multiple endpoints improved with tofacitinib

A Rocky Start for Biosimilar Inflectra?

Infliximab biosimilar approved, but obstacles remain

Knee OA No Excuse to Skip Out on Physical Activity

Patients met thresholds for sit-to-stand, gait speed, and walking speed

Pro Soccer Career: A Risk Factor for Osteoarthritis in Men

Study also suggests controversial joint injections hike OA risk

Reassuring Cancer Data With JIA Tx

No apparent increase in risk with anti-TNF treatment

Two RA Agents Similar in Head-to-Head Trial

Sponsor's hopes of proving Cimzia's superiority to Humira dashed

AHA: Study Finds Celebrex Safe for Heart

But naproxen not as heart safe as believed

Cimzia in New Moms Found Safe for Nursing Babies

Only trace quantities found in breast milk

Pearls From: Rheumatologist Philip Mease

An expert discusses new treatments for PsA and SpA

Tendon Inflammation May Signal Early RA

ACPA positive plus tenosynovitis flag preclinical RA

Outpatient Surgery Safe for Total Hip

No medical or surgical events put patients at risk

Leflunomide Tied to Modest Weight Loss in RA Patients

Weight loss at 6 months linked with higher 3-year mortality

RheumNow: It Took Me 30 Years to Learn This About RA

Jack Cush, MD, shares insights into rheumatoid arthritis

RA Flares Common After Stopping Adalimumab

But anti-TNF discontinuation may be possible in select patients

Steroid Injections May Ease Jaw Pain in JIA

But relief is seldom complete and some patients get no benefit

Some Benefit With Entyvio for Arthritis in Crohn's

Trend seen for treating extraintestinal manifestations

Stroke Spike Seen in Autoimmune Disorders After Shingles Attacks

Risk increased by 50% in the first month

Stelara Eases Spine Symptoms in PsA

Improvements with ustekinumab maintained for 2 years

Squeeze Test in Finger/Toe Joints Won't Diagnose Arthritis

Sensitivity was low for metacarpophalangeal and metatarsophalangeal joints.

Mortality High in Systemic Juvenile Arthritis

Death rates are highest among girls -- up to 50-fold greater than in the general population.

Stopping Enbrel Risky in Established RA

Fewer patients with longstanding disease flared if they remained on even a half dose of etanercept, and time to flare was greater.

Ultrasound After Steroid Shots Helps Slightly in Managing Knee OA

Changes visualized after intra-articular injections are small and of borderline utility.

Stop DMARDs Before Orthopedic Surgery in RA Patients?

Deft medication management is important.

Are RA Patients More Sensitive to Pain?

For many RA is complicated by fibromyalgia.

Meniscus Lesions Tied to Neuropathic Pain in Knee OA

Meniscal extrusion on MRI significantly associated with increasing pain scores in knee osteoarthritis.

Separating Spondyloarthritis From Back Pain Still Problematic

Spinal MRI criteria don't help differentiate SpA from nonspecific pain.

JIA Parents Lose Significant Work Time

More missed work in the year before and after a child's diagnosis of juvenile rheumatoid arthritis.

Painful Hands, Hurting Hearts?

Symptomatic hand osteoarthritis was linked with coronary heart disease.

Women, Blacks at Greater Risk for Bunions

Subgroups most likely to develop hallux valgus confirmed in major study.

NSAID Effective for RA Symptoms, Celebrex Easier on Stomach

Patients on celecoxib experienced greater pain reduction after 6 weeks of treatment.

Does an IUD and Family History Boost RA Risk?

RA-associated autoantibodies tied to IUDs in at-risk women.

Otezla Benefit Durable in PsA

Benefits persist through 2 years with apremilast in psoriatic arthritis.

A Role for the Microbiome for Arthritis in Kids?

Study links antibiotics to JIA risk.

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