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News, opinions and meeting coverage in rheumatology.

FDA Advisers Tackle Epidural Steroid Shots

Focus on adverse neurologic effects.

Humira Benefits Persist in Spine Disease

Anti-TNF treatment efficacy maintained at 3 years in axial spondyloarthritis.

Now What? DEA Tosses Tramadol in Schedule IV

The Drug Enforcement Administration (DEA) scheduled tramadol as a Schedule IV substance -- whats the big fuss about tramadol that led to this decision by the DEA?

How To Tell Fake Neck Pain From Real: The Pain Medicine News Report

A regular update on what鈥檚 new in surgery from our friends at Pain Medicine News.

Medtronic's Infuse Moves From Operating Room to Courtroom

An investigative series by 麻豆传媒/Milwaukee Journal Sentinel has been tracking the spinal fusion device called Infuse in a 4-year-long series and now reports how a flawed FDA system for device approval may have led to a long string of adverse events culminating in thousands of liability suits.

Medtronic Sued by 1,000 Infuse Patients

Medtronic said about 1,000 people have sued the company over its bone morphogenetic protein-2 product, Infuse, and that many more lawsuits may be coming.

Killing Pain: Xanax Tops Charts

Alprazolam, more popularly known by its brand name -- Xanax--is America's favorite tranquilizer and one that is often used in combination with an opioid.

Opioid Use Common After Spine Surgery

NEW ORLEANS -- One year after surgery to relieve back pain, about of third of patients still were using narcotic painkillers, according to a study that raised new concerns about the long-term use of opioids.

FDA Warns of Fatal Skin Reactions with Acetaminophen

SILVER SPRING, Md. -- Acetaminophen is associated with rare but severe and sometimes fatal skin reactions at usual doses, the FDA said Thursday.

FDA Panel Gives Thumbs Down to Opioid

SILVER SPRING, Md. -- An FDA advisory committee voted 11-2 on Friday against recommending approval of a single-entity hydrocodone product, raising questions about its abuse potential.

Drug Relieves Opioid-Induced Constipation

LAS VEGAS -- An investigational opioid antagonist provided effective and durable relief from opioid-induced constipation in patients with chronic pain without interfering with analgesia, a randomized trial showed.

Ablation Possible for Back Pain When Steroid Injections Fail

PALM SPRINGS, Calif. -- Patients with low back pain who don't respond robustly to intraarticular steroid injections may still be candidates for treatment with radiofrequency ablation (RFA), researchers said here.

Short-Acting Opioids May Have Less Impact on Testosterone

PALM SPRINGS, Calif. -- Men who take long-acting opioids for chronic pain may have a higher risk of hypogonadism than those on short-acting formulations of the drugs, researchers said here.

Follow the Money: Pain, Policy, and Profit

When the Federation of State Medical Boards decided it needed to put a model guideline for opioid use into a book, it reached out and touched the makers of opioid drugs to make it happen.

Acetaminophen OD More Deadly if Taken in Stages

Acetaminophen overdoses were more likely to be fatal if patients consumed a series of high doses spread over the course of a day rather than downing, say, a bottle of pills at one time, outcomes among patients admitted to a specialized liver center showed.

Training Technique Stresses Athletes' Spines

CHICAGO --The squat lift, an exercise that has long been a standard training technique for athletes, puts inordinate stress on the spine and likely is the cause of chronic stress fractures in young athletes.

Herniated Disc Surgery Found Cost-Effective

HANOVER, N.H. -- For patients with a herniated disc, surgery proved a cost-effective alternative to nonsurgical treatment over the course of two years, an observational study found.

Scleroderma Patients Are Living Longer

WASHINGTON -- The lifespan for patients with scleroderma has increased significantly since the 1970s, in large measure because of a decline in deaths from renal disease.

Gabapentin (Neurontin) Eases Chronic Pain in Fibromyalgia

CINCINNATI -- For treating the chronic pain and other symptoms of fibromyalgia, the anticonvulsant gabapentin (Neurontin) proved safe and effective, researchers here reported.

Promising Outcomes in Spinal Disc Cadaver Allografts

HONG KONG -- Replacement of degenerative discs in the cervical spine with cadaver allografts shows early promise as an alternative to fusion or artificial discs, found researchers here.

After Meniscectomy, Thigh Muscle Weakness Impairs Knee Function

MALM脙鈥�, Sweden -- Four years after surgery to repair a non-traumatic meniscus tear, loss of muscle strength in the quadriceps left patients with a painful, unstable knee prone to future osteoarthritis, researchers here reported.

ACR: Humira Does Not Affect Flu Vaccination Efficacy

WASHINGTON -- Vaccination against influenza or pneumococcal disease is safe and effective in people with rheumatoid arthritis who are taking Humira (adalimumab), a researcher said here.

High-Dose Steroids Linked to Risk of Atrial Fibrillation

ROTTERDAM, The Netherlands 芒鈧€� High dose corticosteroid therapy may increase the risk of atrial fibrillation, researchers here reported.

Epidural Steroid Injection Not Useful for Chronic Shingles Pain

UTRECHT, The Netherlands - An epidural injection of steroids with a local anesthetic did not provide the long-term pain relief doctors anticipated for patients suffering from post-herpetic neuralgia, researchers here said.

Short-Term Use of High-Dose Ibuprofen Linked to GI Bleeding

HAMILTON, Ontario - Taking high doses of Advil or Motrin (ibuprofen) even for a few days can significantly increase the risk of gastrointestinal bleeding, researchers reported today.

IBD Patients Prone to Other Autoimmune or Inflammatory Disorders

PHILADELPHIA-Patients with the inflammatory bowel disorders ulcerative colitis and Crohn's disease are significantly more likely to suffer from other conditions with an inflammatory or autoimmune basis, said researchers in two separate studies.

Bad News for Cox-2 Inhibitors Was Good News for Mobic

WASHINGTON-The departure of Vioxx (rofecoxib) from pharmacists' shelves last September triggered a boomlet for the NSAID Mobic (meloxicam), which then boosted its prices by 9%, according to a Consumers Union analysis.