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General Rheumatology

News, opinions and meeting coverage in rheumatology.

An x-ray image of a child鈥檚 hands.

These Kids With JIA Fare Poorly for Methotrexate Adherence

Family, social, and financial stress compromises treatment, study suggests

A computer rendering of a syringe releasing monoclonal antibodies.

JAK Inhibitors Edge Out Anti-TNFs for Pain Relief in Rheumatoid Arthritis

Swedish study looks at neglected issue in RA treatment

A photo of a woman鈥檚 legs swollen knees and patches of psoriasis from psoriatic arthritis.

Hitting Psoriatic Arthritis Early With Apremilast Helps Some Patients, Trial Finds

But only a minority achieved minimal disease activity within 16 weeks

FDA APPROVED benralizumab (Fasenra) over a photo of vasculitis rashes on a man鈥檚 leg and foot.

FDA OKs New Option for Rare Immune-Mediated Vasculitis

Benralizumab wins approval for eosinophilic granulomatosis with polyangiitis

A photo of Vice President Richard Nixon and Senator John Kennedy during the 1960 debate.

95-Year-Old Physician: Here's How I Stood Up to a Deeply Ill Richard Nixon

Nixon was still recovering from a difficult infection when he debated JFK in 1960

A computer rendering of an antibody.

Off-the-Shelf Drug Matches CAR-T Effects in Refractory Lupus

Patient achieves remission with biologic agent currently used for myeloma

A photo of a woman self-injecting with an adalimumab injection pen.

Arthritis Patients More Likely to Stick With Biosimilars

Spanish registry data show longer time without discontinuing; reasons unclear, however

A photo of a man鈥檚 hand affected by Raynaud鈥檚 syndrome.

Scleroderma Patients See Worsened Raynaud's in Summer, Too

Study shows surprising nonlinearity between temperature and symptom severity

A computer rendering of a macrophage and blood cells.

Novel Drug Works Near-Miracle for sJIA Patients With Life-Threatening Complication

Compassionate use produces dramatic results in two patients with juvenile idiopathic arthritis

A photo of an IUD lying on a blister pack of birth control pills.

Use of Birth Control Appears Spotty for Women With Lupus

Records suggest guidelines on contraceptives are mostly not followed

A computer rendering of a transparent human body with the kidneys highlighted.

Renal Impairment Tracks With Rheumatoid Arthritis Disease Activity

Study highlights another reason to keep RA under control

A computer rendering of B-cells releasing antibodies.

Combo Biologics for Lupus Mostly Flop

But hint of benefit suggests the approach might not be a dead end

A photo of a variety of medications scattered on $100 bills

Is Medicare's Negotiated Drug Price List Worth Celebrating? Depends on Whom You Ask.

Reactions from physician and consumer groups were positive, but drugmakers begged to differ

Medicare Unveils First 10 Negotiated Drug Prices

Prices slashed by as much as 79%

Methotrexate for Knee Osteoarthritis; Evaluating Squamous Cell Cancers

Also in TTHealthWatch: blood tests for Alzheimer's

A computer rendering of the palmar face of the hand and its contents: median nerve, tendons, radial artery.

Study: Hand OA May Affect Tendons Too

But clinical importance remains uncertain

A photo of a senior woman holding a pill organizer.

Economic, Personal Burden of RA: Maybe Not So Bad?

Survey data show increased healthcare costs, functional impairment, but not as much as expected

A computer rendering of the skeleton and organs of the human body.

Lupus Organ Damage Most Often Comes Early

Spanish cohort study tracked patients for up to 20 years after diagnosis

A photo of a woman drawing from a vial of Remicade.

Medicare Lags, Medicaid Leads for Biosimilar Uptake

Infliximab copycat usage varies widely with payer type

A computer rendering of antibodies around a transparent brain with the basal ganglia highlighted.

Researchers Try to Better Understand PANS/PANDAS

Stanford University group suggests new component to long controversial diagnosis

A photo of a woman with alopecia areata.

Alopecia Areata Tied to Higher Risks of Autoimmune and Psychiatric Comorbidities

This could exacerbate disease burden and reduce quality of life, researchers say

Superior migration of humeral head

Make the Diagnosis: There are Lots of Clues, but Can You Make the Diagnosis?

A 68-year-old man presented to the doctor with complaints of right shoulder pain, joint stiffness, and decreased range of motion that developed over the last 2 months. Can you diagnose the patient?

A photo of row houses in Philadelphia.

Poor Neighborhood, More Than Race, Predicts Greater Lupus Skin Severity

Blackness, per se, seen as less important than area socioeconomics

A computer rendering of a transparent body with the kidneys highlighted.

This Drug Class Keeps AA Amyloidosis in Check

Staves off end-stage renal disease, retrospective study indicates

A photo of smog over London.

Genes, Air Pollution Combine to Raise Lupus Risk

British data suggest how environmental and genetic factors add together

A distorted Amsler grid over a photo of an eye.

Rheumatology Meds Seen Cutting AMD Risk

Claims data point to possible protective effect for one common drug class

A photo of a mature woman鈥檚 knee x-ray on a monitor as she meets with a female rheumatologist in the background.

Osteoarthritis Diagnosis Portends Sickly Later Life

20-year study portrays OA as risk factor for multiple comorbidity

A computer rendering of periodontitis.

Wait, Maybe Periodontal Disease Doesn't Promote Rheumatoid Arthritis (or Vice Versa)

Danish study suggests surprising explanation for association

A photo of a woman wearing an apron carrying a frozen pizza on a baking sheet.

Do Ultraprocessed Foods Increase Lupus Risk for Women?

Sobering findings from Nurses' Health Study

A photo of a man鈥檚 hand inflamed by systemic lupus erythematosus

Could Two Targeted Therapies Be Better Than One in Lupus?

Mid-stage trial tests a JAK inhibitor as monotherapy and in combination with a BTK blocker

A close up photo of broccoli soup.

Really, Soup Might Help in Osteoarthritis?

Not just any soup. And no chicken needed.

A photo of a prescription bottle of metformin tablets next to a glucose monitor.

Lupus Complications Reduced With Common Diabetes Drug

Metformin benefits seen extending way beyond its glucose-lowering properties

A computer rendering of test tubes of blood lying on a test form.

Use This Common Cardiac Test in RA Patients, Study Suggests

Identifies heart risks not captured by conventional risk factors

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

SpA Patients Do Just Fine Managing Their Own Follow-Up Care

Randomized trial suggests usual practice is wasteful

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Izokibep Marches on for Psoriatic Arthritis

Early phase III data cement case for novel IL-17A inhibitor

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Novel URAT1 Inhibitors Advance for Gout

New treatment options on the horizon come into better focus

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

OA Patients Get Long-Term Benefit From Lifestyle Improvements

Improvement in pain and function lasted well after formal program ended

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Is 'Difficult-to-Treat' RA a Lost Cause?

The name says it all, but progress appears to be coming

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

CAR-T Treatment Continues to Astonish in Rheumatologic Diseases

Numbers of patients, length of follow-up keep growing with no visible downside (yet)

A close up photo of a Humira prefilled syringe.

Humira Clobbers Biosimilars in Battle for Part D Coverage

Pricing, payer policies keep market leader on top

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