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General Rheumatology

News, opinions and meeting coverage in rheumatology.

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

Study: Statins Mitigate Heart Risks From JAK Inhibitors

Is this the final finding from ORAL Surveillance? Don't count on it.

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

Multimarker Urine Test Promises to Improve Lupus Nephritis Diagnosis, Prognosis

Accuracy above 85% in early testing -- far better than proteinuria and biopsy

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

Is It the Therapy or the Therapist Who Helps With Knee Pain?

Physical therapy for meniscal tears clearly helps, but new study points to a placebo effect

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

Two Treatments That Don't Work for Osteoarthritis

Negative studies of colchicine and herbal-supplement cocktail dash some hopes

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

Zoster Vaccine Found Effective, Safe in Autoimmune Patients

Claims data show it works and doesn't cause lupus flares

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

JAK Inhibitor Succeeds in Giant Cell Arteritis Trial

At least modestly effective, phase III data show

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

NMO Drug Looks Good for IgG4-Related Disease

Phase III results, now published, should support approval

The YouTube thumbnail with a cartoon man in scrubs holding a piggy bank next to the number $244,517.

Lowest Paid Medical 麻豆传媒 in 2024

These eight specialties earn the least, with many averaging less than $300k per year

A photo of a female physical therapist guiding her senior female client through resistance band exercises.

Resistance Training Falls Short in Severe Hip Arthritis

Trial finds conservative approach inferior to joint replacement

A night shot of downtown Birmingham Alabama.

Surprising Mediator Links Poverty and Knee Pain

Study: It's not deprivation per se, but intervening factors that go with it

A photo of bottles of Jyseleca tablets.

Filgotinib Maintains RA Efficacy for 3 Years, No New Safety Issues

Looks like FDA blew the call on selective JAK1 inhibitor

A photo of a female orthopedic doctor performing an ultrasound on a little girl鈥檚 knee.

Old-Line Rheum Drugs Lose Luster in JIA

Treatment patterns shift as new products come on board

A computer rendering of a knee joint highlighted in red.

Another Stab at Disease-Modifying OA Drug Hits Home in Early Study

Taking a page from HIV medicine

A photo of a senior man receiving a COVID vaccination.

Study Offers Clues for Avoiding RMD Flares After COVID Vaccination

European registry analysis brings surprises along with the expected

A scanning electron microscope image of uric acid crystals.

Want to Cut Urate Levels? Try Losing Weight

But Japanese study suggests losses need to be substantial

A photo of a woman running in a park.

This Exercise May Help Lower Back Pain, No Special Equipment Needed

Carefully structured run-walk program proves mettle in small trial

MRI images of sacroiliac articulation in a patient with ankylosing spondyloarthritis.

AI Does OK, Not Great, for Finding Inflamed Joints in axSpA

While imperfect relative to human experts, system might still be clinically useful

A photo of a female physiotherapist leading a man through knee exercises in a gym.

Exercise, Education to Relieve Knee OA: Mixed Results in Modeling Study

Only limited value when costs are considered, study suggests

A photo of an MRI image of a knee on a monitor with an out-of-focus MRI machine in the background.

In Diagnosing Knee Pain, Sometimes More Is More

MRI does occasionally reveal important findings missed on x-ray

An x-ray image of a child鈥檚 hands.

These Kids With JIA Fare Poorly for Methotrexate Adherence

Family, social, and financial stress compromises treatment, study suggests

A computer rendering of a syringe releasing monoclonal antibodies.

JAK Inhibitors Edge Out Anti-TNFs for Pain Relief in Rheumatoid Arthritis

Swedish study looks at neglected issue in RA treatment

A photo of a woman鈥檚 legs swollen knees and patches of psoriasis from psoriatic arthritis.

Hitting Psoriatic Arthritis Early With Apremilast Helps Some Patients, Trial Finds

But only a minority achieved minimal disease activity within 16 weeks

FDA APPROVED benralizumab (Fasenra) over a photo of vasculitis rashes on a man鈥檚 leg and foot.

FDA OKs New Option for Rare Immune-Mediated Vasculitis

Benralizumab wins approval for eosinophilic granulomatosis with polyangiitis

A photo of Vice President Richard Nixon and Senator John Kennedy during the 1960 debate.

95-Year-Old Physician: Here's How I Stood Up to a Deeply Ill Richard Nixon

Nixon was still recovering from a difficult infection when he debated JFK in 1960

A computer rendering of an antibody.

Off-the-Shelf Drug Matches CAR-T Effects in Refractory Lupus

Patient achieves remission with biologic agent currently used for myeloma

A photo of a woman self-injecting with an adalimumab injection pen.

Arthritis Patients More Likely to Stick With Biosimilars

Spanish registry data show longer time without discontinuing; reasons unclear, however

A photo of a man鈥檚 hand affected by Raynaud鈥檚 syndrome.

Scleroderma Patients See Worsened Raynaud's in Summer, Too

Study shows surprising nonlinearity between temperature and symptom severity

A computer rendering of a macrophage and blood cells.

Novel Drug Works Near-Miracle for sJIA Patients With Life-Threatening Complication

Compassionate use produces dramatic results in two patients with juvenile idiopathic arthritis

A photo of an IUD lying on a blister pack of birth control pills.

Use of Birth Control Appears Spotty for Women With Lupus

Records suggest guidelines on contraceptives are mostly not followed

A computer rendering of a transparent human body with the kidneys highlighted.

Renal Impairment Tracks With Rheumatoid Arthritis Disease Activity

Study highlights another reason to keep RA under control

A computer rendering of B-cells releasing antibodies.

Combo Biologics for Lupus Mostly Flop

But hint of benefit suggests the approach might not be a dead end

A photo of a variety of medications scattered on $100 bills

Is Medicare's Negotiated Drug Price List Worth Celebrating? Depends on Whom You Ask.

Reactions from physician and consumer groups were positive, but drugmakers begged to differ

Medicare Unveils First 10 Negotiated Drug Prices

Prices slashed by as much as 79%

Methotrexate for Knee Osteoarthritis; Evaluating Squamous Cell Cancers

Also in TTHealthWatch: blood tests for Alzheimer's

A computer rendering of the palmar face of the hand and its contents: median nerve, tendons, radial artery.

Study: Hand OA May Affect Tendons Too

But clinical importance remains uncertain

A photo of a senior woman holding a pill organizer.

Economic, Personal Burden of RA: Maybe Not So Bad?

Survey data show increased healthcare costs, functional impairment, but not as much as expected

A computer rendering of the skeleton and organs of the human body.

Lupus Organ Damage Most Often Comes Early

Spanish cohort study tracked patients for up to 20 years after diagnosis

A photo of a woman drawing from a vial of Remicade.

Medicare Lags, Medicaid Leads for Biosimilar Uptake

Infliximab copycat usage varies widely with payer type

A computer rendering of antibodies around a transparent brain with the basal ganglia highlighted.

Researchers Try to Better Understand PANS/PANDAS

Stanford University group suggests new component to long controversial diagnosis

A photo of a woman with alopecia areata.

Alopecia Areata Tied to Higher Risks of Autoimmune and Psychiatric Comorbidities

This could exacerbate disease burden and reduce quality of life, researchers say

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