Adding AKT Inhibitor Doubles PFS in Advanced, HR-Positive Breast Cancer In phase III trial, capivasertib benefited patients with or without AKT pathway alterations Dec 09, 2022
Oral SERD Tops Fulvestrant for PFS in ER-Positive Breast Cancer Camizestrant also led to meaningful PFS improvements in those with detectable ESR1 mutations Dec 09, 2022
Pharmacogenomic Results Clear to Young Cancer Patients' Families But few guardians shared these results with other care providers Dec 09, 2022
Small Study Shows Most Crohn's Patients With Anal Cancer Survived 15 of 24 were alive and cancer free at 5.5 years of follow-up Dec 09, 2022
Continuing CDK4/6 Inhibitor Beyond Progression No Help in Metastatic Breast Cancer Prior therapy, baseline mutations confound results; "intriguing" benefit with PD-L1 inhibitor Dec 09, 2022
Pausing Endocrine Therapy for Pregnancy Safe in Early Breast Cancer Study suggests no increased risk of cancer recurrence versus historical control Dec 09, 2022
T-DXd Continues Winning Streak in Metastatic, HER2-Positive Breast Cancer Trastuzumab deruxtecan improves survival in second- and later-line settings Dec 08, 2022
Neoadjuvant T-DXd Active in HER2-Low Breast Cancer Response rates on the order of 58-68%, with or without endocrine therapy Dec 08, 2022
Can Just Minutes of Daily Activity Prolong Life? Benefits included all-cause, heart, and cancer-related mortality risk reduction Dec 08, 2022
Everolimus Fails Again as Adjuvant Therapy for High-Risk Breast Cancer No improvement in the overall analysis but a hint of benefit in premenopausal patients Dec 08, 2022
Assay Predicts Breast Cancer Patients Who Will Benefit From Ovarian Suppression Low score suggests improved outcomes with ovarian suppression plus adjuvant endocrine therapy Dec 07, 2022
First-Line CDK4/6 Thumps Chemo in Aggressive, Advanced Breast Cancer Doubling of PFS could be death knell for combination chemotherapy in difficult-to-treat subgroup Dec 07, 2022
MRI-Targeted Biopsy for Prostate Cancer Reduces Risk of Overdiagnosis Though at the cost of delayed diagnosis of some clinically significant cancers Dec 07, 2022
Metastasis 'Doorway' May Lead to Racial Disparities in Breast Cancer Density of cellular complex after neoadjuvant therapy tied to cancer subtypes, may be targetable Dec 07, 2022
Cost Savings With Pharmacist-Driven Substitutions of Oncology Biosimilars Regional clinical pharmacists helped community oncology practices navigate logistics, financials Dec 07, 2022
Xeljanz Cancer Risks Detailed New paper provides full results from ORAL Surveillance trial Dec 07, 2022
I'm a Neurologist, Hear Me Roar If I wasn't believed when seeking care, what chance do non-physicians have? Dec 06, 2022
Decoding Cancer A conversation with Harold Varmus, MD, who received the Nobel Prize in Physiology or Medicine in 1989 Dec 06, 2022 podcast
Can Oncologists Reduce the Suicide Risk in Their Prostate Cancer Patients? Barriers exist in identifying risk, but strategies are available Dec 06, 2022
Aging U.S. Population a Challenge for Oncologists Older patients will have different care goals, preferences, geriatric oncologist says Dec 05, 2022
Year in Review: Acute Lymphoblastic Leukemia New ways to use CAR T-cell therapy and treatment de-intensification strategies Dec 05, 2022
To Combat Opioid Epidemic, Step Up Safe Prescribing Practices, Expert Urges Overprescribing a continuing problem, Benjamin Davies tells urologists Dec 02, 2022
Pre-Op Axitinib Helps for Partial Nephrectomy of Complex Renal Tumors Approach in small ongoing trial resulted in reduction in tumor size and complexity Dec 02, 2022
Sequential Gemcitabine/Docetaxel Promising in NMIBC After BCG Relapse But patients with BCG-refractory disease may be better suited for cystectomy Dec 02, 2022
New IDH1 Inhibitor Wins FDA Approval for Acute Myeloid Leukemia Olutasidenib led to a 35% response rate in a study of adults with previously treated AML Dec 02, 2022
Still Using Medical Jargon? Prepare to Be Misunderstood Survey shows just how often individuals misinterpret common medical phrases Dec 01, 2022
Metastasis-Directed Therapy May Delay ADT in Advanced Prostate Cancer Surgery or radiation delayed initiation of systemic therapy by 18 months Nov 29, 2022
Life and Death in 12 Hours ICU nurse Christin Thankachan on providing comfort during life's darkest moments Nov 29, 2022 podcast
Lung Cancer Survival High for Patients With Early, Screen-Detected Tumors Two decades of I-ELCAP follow-up data show 80% lung cancer-specific survival rate Nov 28, 2022
Robotic Surgery Proves Its Mettle for Liver Cancer Fewer cases of liver failure, similar survival versus open liver resection in matched analysis Nov 23, 2022
Persistent Lymphadenopathy and Neck Abscesses in a Healthy Boy Histopathological test results were central to ultimate diagnosis Nov 23, 2022
FDA OKs First Gene Therapy for Hemophilia B Hemgenix reduced rate of annual bleeds, eliminated need for factor IX prophylaxis therapy Nov 22, 2022
Exercise During Chemo Shows Benefits for Cardiorespiratory Fitness However, patients who exercise after chemo also ultimately see benefits too Nov 21, 2022
RT After Breast-Conserving Surgery Shows No Survival Advantage Decades Later But "that's not the intent of radiation therapy," says outside expert Nov 18, 2022
Year in Review: Hemophilia Gene therapy continues to show promise in clinical trials, but is it ready for the clinic? Nov 17, 2022
Primary Care Visits Prior to Cancer Diagnosis Tied to Lower Mortality Most benefit with annual visits, but even some use linked to better outcomes Nov 16, 2022
Melanoma Resistant to Anti-PD-1 Responds to Tumor Infiltrating Lymphocytes Almost a third of patients had objective responses, which deepened over time, study showed Nov 16, 2022
AMA Votes to Oppose Punishing Doctors When Necessary Care Results in Fetal Death Doctors recount horrors of physician and patient arrests after loss of pregnancy Nov 15, 2022
Allogeneic CAR T-Cell Therapy Shows Early Promise in Kidney Cancer CTX130 yields sustained complete response in one patient with relapsed/refractory disease Nov 15, 2022
