Enfortumab Vedotin Promising in Neovadjuvant Therapy in Advanced Bladder Cancer Early-phase study offers 36% pCR in cisplatin-ineligible patients with muscle-invasive disease Feb 19, 2022
Ablating High-Grade Anal Lesions Thwarts Progression to Cancer Screening followed by aggressive therapy shows benefit in phase III ANCHOR study Feb 17, 2022
Sotorasib Impresses in Advanced Pancreatic Cancer ORR of 21% in heavily pretreated patients with a KRAS G12C mutation Feb 16, 2022
Women More Likely to Experience Severe Toxicity of Cancer Treatments Increased risk was particularly pronounced among those receiving immunotherapy Feb 14, 2022
Pembrolizumab Shows Promise in Advanced Anal Cancer PD-1 inhibitor may be an option for those who have no options Feb 11, 2022
Uterine Cancer Mortality Now Neck and Neck With Ovarian Cancer Advances in ovarian cancer, stagnation in uterine cancer, and "alarming" racial disparity Feb 09, 2022
Genetic Role of Alcohol-Cancer Link Strengthened In study from China, two common variants associated with lower risk of cancer in men Feb 01, 2022
When Strangers Deliver Bad News to Patients All too often, I end up giving prognoses to patients I barely know Jan 31, 2022
An 'Intriguing Failure' in Advanced, Pre-Treated GIST Second-line ripretinib unable to best sunitinib, but still had meaningful clinical activity Jan 26, 2022
Trial Data Confirm Heightened Risks With JAK Inhibitor May help patients and clinicians better weigh benefit against adverse effects Jan 26, 2022
Paclitaxel-Carboplatin Established as Standard of Care for Uterine Carcinosarcoma Median OS and PFS improved versus paclitaxel-ifosfamide Jan 25, 2022
GICS Roundup: PD-1 Inhibitor Yields 100% Response Rate in dMMR Rectal Cancer Plus: Promising activity in BRAF-mutant CRC, L-asparaginase drug falls short in pancreatic cancer Jan 24, 2022
Adagrasib Promising in KRAS-Mutant GI Cancers The KRAS G12C inhibitor showed a disease control rate of 100% in small study Jan 24, 2022
Survival Bump in Biliary Cancer With Immunotherapy Plus Chemotherapy Adding durvalumab boosts OS by 1.3 months, first survival improvement in a decade Jan 23, 2022
Potential New First-Line Options for Unresectable Hepatocellular Carcinoma Tremelimumab-durvalumab improves OS, single-agent durvalumab non-inferior to sorafenib Jan 22, 2022
Pre-Op Immunotherapy Combo Makes Headway in Select Gastric Cancers Plus, novel bispecific antibody tested as first-line therapy for advanced gastric/GEJ cancer Jan 21, 2022
More Data for Upfront PD-1 Inhibition in Gastric, Esophageal Cancer Updates from two landmark trials show consistent benefits across subgroups, PD-L1 expression Jan 21, 2022
Growing Controversy Over 'Skinny' Labeling for Generic Drugs What's at stake in legal battles over patent-avoiding approval pathway for generics Jan 17, 2022
Living History: 50 Years After the Birth of National Cancer Centers New book examines the progress 50 years following the National Cancer Act of 1971 Dec 22, 2021
Virgil Abloh's Cardiac Angiosarcoma The fashion designer's death due to this rare form of cancer took the world by surprise Dec 15, 2021
Gene Therapy Resolves Severe Pain Events in Sickle Cell Disease LentiGlobin also normalized hemoglobin and reduced hemolysis markers Dec 15, 2021
In the Story of Our Practice, We're Always the Hero When is it right to challenge our medical colleagues? Dec 14, 2021
Ξ²-Thalassemia Patients Go Transfusion-Free With Gene Therapy Treatment with beti-cel is "potentially curative" in this transfusion-dependent group Dec 13, 2021
BRAF Inhibition in Pediatric Ameloblastoma of the Jaw Targeted therapy in 3 boys allowed for conservative surgery to restore jaw to predisease state Dec 07, 2021
Hemostatic Powder on Par for Stopping Acute Upper GI Bleeds In non-inferiority trial, TC-325 matched standard therapy for nonvariceal lesions Dec 07, 2021
But the Cancer Was 'Indolent' Tread carefully when offering patients an optimistic outlook Dec 07, 2021
Novel Chemoimmunotherapy Regimen Wows in Pediatric Neuroblastoma "I've never seen anything like this," researcher says of 3-year event-free survival rate Dec 06, 2021
States Didn't Follow CDC Recs to Prioritize COVID Vaccine for Cancer Patients Only 17 states gave cancer patients the same immunization priority as those ages 65-74 Dec 02, 2021
'Actual' 5-Year Survival Rate of 27% After Surgery, Chemo for Pancreatic Cancer Fewer than half of the survivors remained recurrence- or disease-free Nov 19, 2021
Ceritinib Shows Promise in ALK-Positive Pediatric Malignancies Responses seen in neuroblastoma, among other tumors Nov 17, 2021
Tumor Spill Common in Minimally Invasive Hysterectomies for Endometrial Cancer Few surgeons in survey reported changing post-op management after spillage Nov 16, 2021
Chemo-ICI Combo Promising in Soft Tissue Sarcoma PFS rate of 69% at 12 weeks in liposarcoma patients with eribulin and pembrolizumab Nov 14, 2021
Active Surveillance Still the Best Bet in Desmoid-Type Fibromatosis GRAFITI trial show's less than a third of watched patients eventually need active treatment Nov 13, 2021
T-Cell Therapy Shows Promise in Rare Sarcomas Afami-cel induced durable responses in synovial sarcoma and myxoid/round cell liposarcoma Nov 12, 2021
Preterm Birth Drug Tied to Cancer Risk in Those Exposed in Utero Mothers who took 17-OHPC for miscarriage in the 1950s and 1960s had offspring at greater risk Nov 12, 2021
High COVID Complication Rates in Sarcoma Patients Half of patients in registry-based study were hospitalized Nov 12, 2021
Ripretinib Continues to Demonstrate Benefit in Advanced GIST Updated analysis shows stable PFS, improved OS Nov 11, 2021
Benzene Found in Spray Deodorants Now Too, Valisure Says Online pharmacy has previously petitioned FDA regarding contaminated hand sanitizers, sunscreens Nov 05, 2021
Primary RT Fares Well in Abbreviated Trial for HPV Oropharyngeal Cancer No deaths, progression with RT after early termination because of deaths in surgery arm Oct 29, 2021
Pathologists Consider 'Workaround' So Patients Don't Freak Out Over EHR Bad News Doctors worry patients will misconstrue language or be psychologically harmed without guidance Oct 28, 2021
