Adagrasib Promising in KRAS-Mutant GI Cancers The KRAS G12C inhibitor showed a disease control rate of 100% in small study Jan 24, 2022
Survival Bump in Biliary Cancer With Immunotherapy Plus Chemotherapy Adding durvalumab boosts OS by 1.3 months, first survival improvement in a decade Jan 23, 2022
Potential New First-Line Options for Unresectable Hepatocellular Carcinoma Tremelimumab-durvalumab improves OS, single-agent durvalumab non-inferior to sorafenib Jan 22, 2022
Pre-Op Immunotherapy Combo Makes Headway in Select Gastric Cancers Plus, novel bispecific antibody tested as first-line therapy for advanced gastric/GEJ cancer Jan 21, 2022
More Data for Upfront PD-1 Inhibition in Gastric, Esophageal Cancer Updates from two landmark trials show consistent benefits across subgroups, PD-L1 expression Jan 21, 2022
Growing Controversy Over 'Skinny' Labeling for Generic Drugs What's at stake in legal battles over patent-avoiding approval pathway for generics Jan 17, 2022
Living History: 50 Years After the Birth of National Cancer Centers New book examines the progress 50 years following the National Cancer Act of 1971 Dec 22, 2021
Virgil Abloh's Cardiac Angiosarcoma The fashion designer's death due to this rare form of cancer took the world by surprise Dec 15, 2021
Gene Therapy Resolves Severe Pain Events in Sickle Cell Disease LentiGlobin also normalized hemoglobin and reduced hemolysis markers Dec 15, 2021
In the Story of Our Practice, We're Always the Hero When is it right to challenge our medical colleagues? Dec 14, 2021
Ξ²-Thalassemia Patients Go Transfusion-Free With Gene Therapy Treatment with beti-cel is "potentially curative" in this transfusion-dependent group Dec 13, 2021
BRAF Inhibition in Pediatric Ameloblastoma of the Jaw Targeted therapy in 3 boys allowed for conservative surgery to restore jaw to predisease state Dec 07, 2021
Hemostatic Powder on Par for Stopping Acute Upper GI Bleeds In non-inferiority trial, TC-325 matched standard therapy for nonvariceal lesions Dec 07, 2021
But the Cancer Was 'Indolent' Tread carefully when offering patients an optimistic outlook Dec 07, 2021
Novel Chemoimmunotherapy Regimen Wows in Pediatric Neuroblastoma "I've never seen anything like this," researcher says of 3-year event-free survival rate Dec 06, 2021
States Didn't Follow CDC Recs to Prioritize COVID Vaccine for Cancer Patients Only 17 states gave cancer patients the same immunization priority as those ages 65-74 Dec 02, 2021
'Actual' 5-Year Survival Rate of 27% After Surgery, Chemo for Pancreatic Cancer Fewer than half of the survivors remained recurrence- or disease-free Nov 19, 2021
Ceritinib Shows Promise in ALK-Positive Pediatric Malignancies Responses seen in neuroblastoma, among other tumors Nov 17, 2021
Tumor Spill Common in Minimally Invasive Hysterectomies for Endometrial Cancer Few surgeons in survey reported changing post-op management after spillage Nov 16, 2021
Chemo-ICI Combo Promising in Soft Tissue Sarcoma PFS rate of 69% at 12 weeks in liposarcoma patients with eribulin and pembrolizumab Nov 14, 2021
Active Surveillance Still the Best Bet in Desmoid-Type Fibromatosis GRAFITI trial show's less than a third of watched patients eventually need active treatment Nov 13, 2021
T-Cell Therapy Shows Promise in Rare Sarcomas Afami-cel induced durable responses in synovial sarcoma and myxoid/round cell liposarcoma Nov 12, 2021
Preterm Birth Drug Tied to Cancer Risk in Those Exposed in Utero Mothers who took 17-OHPC for miscarriage in the 1950s and 1960s had offspring at greater risk Nov 12, 2021
High COVID Complication Rates in Sarcoma Patients Half of patients in registry-based study were hospitalized Nov 12, 2021
Ripretinib Continues to Demonstrate Benefit in Advanced GIST Updated analysis shows stable PFS, improved OS Nov 11, 2021
Benzene Found in Spray Deodorants Now Too, Valisure Says Online pharmacy has previously petitioned FDA regarding contaminated hand sanitizers, sunscreens Nov 05, 2021
Primary RT Fares Well in Abbreviated Trial for HPV Oropharyngeal Cancer No deaths, progression with RT after early termination because of deaths in surgery arm Oct 29, 2021
Pathologists Consider 'Workaround' So Patients Don't Freak Out Over EHR Bad News Doctors worry patients will misconstrue language or be psychologically harmed without guidance Oct 28, 2021
Gentler Adjuvant RT Could Be Viable for Some HPV-Positive Oral Cancers Those with extranodal extension didn't fare as well Oct 27, 2021
Rare Aggressive Bladder Cancer Treated Successfully in Elderly Man Neoadjuvant chemotherapy followed by cystectomy achieves complete response Oct 21, 2021
A Better Option for Preserving Fertility in Gynecologic Cancer Patients? In vitro maturation can result in both embryos and oocyte vitrification, researcher says Oct 19, 2021
The Price Tag of FDA's 'Onco-Exceptionalism' Substantial use of certain cancer drugs without an overall survival benefit Oct 18, 2021
Abiraterone Active in Androgen Receptor-Positive Salivary Tumors Disease control in 62.5% of a small cohort, including five partial responses Oct 14, 2021
What Happens When All the Great Doctors Are Gone? In commemoration of the late Elihu (Eli) Estey, MD Oct 13, 2021
What's the Best Way to Treat Femur Breaks From Bone Metastases? No difference in outcomes between long-stem hemiarthroplasty and intramedullary nailing Oct 10, 2021
Pediatric Sarcoma Patients Face Late Amputation Risk Decades Later Study finds about 18% required amputation long after initial limb salvage surgery Oct 09, 2021
Take Sarcoma Research Based on Registry Data With a Grain of Salt Many studies using SEER/NCDB registries often generated disparate outcomes Oct 08, 2021
No Benefit for Longer-Duration Antibiotic Prophylaxis After Limb Salvage Surgical site infections similar versus shorter-duration prophylactic IV regimen Oct 08, 2021
Antibiotic Could Thwart Costly Sarcoma Surgery Complication Benefit seen for adding "anaerobic coverage" to standard perioperative antibiotic prophylaxis Oct 07, 2021
