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Data too uncertain to support sotagliflozin in subset with chronic kidney disease, advisors say

Health news and commentary gathered by 麻豆传媒 staff

SGLT1/SGLT2 inhibitor has another shot in T1D, but now in more narrow patient population

Deadly E. coli outbreak has been tentatively traced to contaminated onions

However, 24 weeks of the GLP-1 had no impact on eGFR

Personalized recs were made by team of physicians and pharmacists within an hour of diagnosis

Trial follow-up defines the need for long-term treatment in protecting the kidneys and heart

Observational study points to genetic risk allele dose-response

Anti-mineralocorticoid agent reduced albuminuria, but not eGFR-based kidney outcome

Ravulizumab reduced proteinuria, stabilized eGFR in IgA nephropathy

Surrogate endpoint of urinary protein-to-creatinine ratio "widely considered to be predictive"

Treatment with iptacopan reduces proteinuria in interim APPLAUSE-IgAN analysis

Study also raises question of antibiotic prophylaxis in kids with common congenital anomaly

Study details an intermediate prognosis with newer microvascular inflammation phenotypes