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General Neurology

News, opinions and meeting coverage in neurology.

AAN over a photo of the Boston Convention and Exhibition Center in Boston, MA.

Novel MS Drug Good as Gold in Phase II Study

Yes, we mean element no. 79 on the periodic table

A photo of a container of gummies.

Melatonin Gummies May Not Be What They Claim to Be

Nearly 90% of brands were mislabeled, lab analysis shows

A photo of nurses tending to a COVID patient in the intensive care unit.

Myasthenia Gravis Tied to Elevated Risk for Severe COVID

Patients with autoimmune disorder should be prioritized for vaccines, antivirals, researchers say

AAN over a photo of the Boston Convention and Exhibition Center in Boston, MA.

Stroke Prevalence Inches Upward in American Men

Slight uptick in males since 1999, but other demographic groups remain stable

AAN over a photo of the Boston Convention and Exhibition Center in Boston, MA.

Hints of Benefit for Novel Post-Herpetic Pain Drug

Phase II study misses primary endpoint, but likely to move forward anyway

AAN over a photo of the Boston Convention and Exhibition Center in Boston, MA.

Pilots Hide Health Problems to Avoid Losing Certification, Survey Shows

May see disincentives to be truthful about their health

A photo of a blind man using a cane to cross a street with a woman on his arm.

Man Goes Blind After Binging on Booze and Crystal Meth

Look beyond uremia and acidosis for rare cause of lentiform fork sign on MRI, authors say

A photo of a boy suffering from autism sitting at a desk in a special needs school.

Will Proposed ACGME Requirements Have Consequences for Kids With Autism?

More strategic and thoughtful updates are necessary

A photo of a mature woman sitting on the edge of her bed in a dark room.

Alzheimer's Proteins Reduced by Sleep Drug

Both amyloid and tau levels fell in early trial

AAN over a photo of the Boston Convention and Exhibition Center in Boston, MA.

Exciting Early Results With Novel Cell Therapy for Focal Epilepsy

First two recipients show dramatic reductions in seizure frequency

A photo of a bottle of 60 mg Qulipta tablets over a photo of a woman wincing with her fingers pressing her temples.

Oral Agent Shows Promise in Treatment-Resistant Migraine

Gepant reduced number of monthly migraine days

A photo of a senior man performing a memory test while sitting across a desk from a male physician.

Test Predicts Transition From Normal to Impaired Cognition

Sensitive, simple test detects subtle deficit at its earliest stage

A photo of a cerebral oximeter attached to the forehead of an infant.

Cerebral Oximetry Not a Lifesaver for Extremely Preterm Infants

No significant changes in death or brain injury in NICU patients

A computer rendering of antibodies attacking COVID viruses.

Long COVID Neuro Symptoms May Be Shaped by Exposure to Other Coronaviruses

Findings suggest possible role of original antigenic sin

A photo of a male cardiac surgeon performing catheter ablation on a patient with atrial fibrillation

RF Ablation or Drugs for Afib: Choice May Matter for Cognitive Outcomes

New study suggests one does a better job of protecting the brain

A 3D printed covid spike protein in front of a 3D printed COVID virus.

SARS-CoV-2 Spike Protein Accumulates in the Skull and Brain

Whether findings have implications for long COVID is unclear

A photo of prescription bottles of pain medication sitting on the edge of a bathroom sink.

Chronic Pain Affects 21% of Americans, CDC Reports

Nearly 7% have pain severe enough to restrict daily activities

A photo of blue rubber gloved hands holding an assay plate.

Parkinson's Biomarker Shows High Accuracy

Assay identifies hallmark protein and could help diagnose people earlier

A photo of a male physician listening to his female patient.

Functional Neurological Disorder May Still Carry Stigma

FND is a feminist issue, researchers and clinicians maintain

Prepare for the Worst, Hope for the Best

Pediatric neurologist braces himself for worst case scenario

A photo of a mother holding her baby who suffers from microcephaly

Brain Injury Seen in Two Neonates Whose Mothers Had COVID

Infants were born early in the pandemic, before COVID vaccines were available

A computer rendering of a CAR-T cell attacking a cancer cell.

CAR T-Cell Therapy Feasible, Safe in Advanced Neuroblastoma

ORR of 63% with GD2-targeting product in kids with relapsed, refractory high-risk disease

Neuro Break over a computer rendering of neurons.

Detecting Alzheimer's in Speech; Manipulating CSF in Humans; Gut Microbiome and MS

News and commentary from the world of neurology and neuroscience

A computer rendering of of amyloid plaques affecting neurons and neurofibrillary tangles inside neurons

Brains Shrink With Anti-Amyloid Alzheimer's Drugs

Treatments accelerate brain atrophy, but reasons why remain a mystery

A medical illustration of the concept of circadian rhythm with a cut away human looking at the sun

Cluster Headache, Migraine Linked to Circadian System

Findings may influence treatment approaches for some patients

A photo of Tamia Potter

Potter Will Be Vanderbilt's First Black Female Neurosurgery Resident

A first since neurosurgery program opened in 1932

A photo of two bottles of Wakix tablets, 4.5 mg and 17.8 mg, and their packaging.

Pitolisant Safe and Effective in Children With Narcolepsy

First study in a pediatric population, with findings similar to adults

A computer rendering of covid viruses around a human brain

Functional Neurological Disorder Emerges After COVID Infection, Vaccines

Long COVID functional manifestations differ from post-vaccine effects

A photo of a female psychologist evaluating a little boy with autistic behaviors.

Autism Prevalence Is Up, CDC Report Shows

But early evaluations in young children started to fall as pandemic set in

FDA APPROVED tofersen over a computer rendering of a damaged motor neuron.

FDA Panel Supports Tofersen for Rare Genetic ALS

In a first, agency advisors back neurofilament light as a surrogate endpoint

FDA ADCOMM tofersen over a computer rendering of a damaged motor neuron.

Investigational ALS Drug May Have Clinical Benefit, FDA Staff Says

Neurofilament light will be evaluated as a surrogate endpoint in tofersen review

A photo of a young female physician standing at the bedside of her senior female patient.

Post-Op Delirium Linked to Accelerated Cognitive Decline

Cognitive trajectory showed consistent pattern for most of 6-year follow-up

AAOS over a photo of the Venetian Sands Expo Center in Las Vegas, Nevada.

More Data Suggest Concussion Raises Leg Injury Risk

Causality still unclear but getting harder to argue against

MRI images of the fetus inside the infant鈥檚 skull next to photos of the fetus removed.

Fetus Removed From Brain of 1-Year-Old Girl

Intracranial fetus-in-fetu identified in child with motor delay

A photo of a man laying on a gurney attached to a temperature management system.

Longer Temperature Management No Better After Cardiac Arrest

Device-based fever prevention beyond 36 hours shows no mortality or disability benefits

A photo of a pregnant woman laying on the couch blowing her nose.

Study Reassures on Asthma Med Use in Pregnancy and Kids' Neuropsych Risks

Use of leukotriene-receptor antagonists not tied to risks of ADHD, autism, Tourette syndrome

A photo of a worried-looking senior woman sitting at a table next to a window.

Incident Cognitive Impairment Tied to Stress

More than one in five older adults report high levels of perceived stress

A photo of a Houston Texans football player injured on the field.

NFL Concussion Symptoms Tied to Cognitive Function Decades Later

Players with concussion symptoms performed worse on cognitive tests as they aged

A photo of a man in a wheelchair showing his wife his phone as they sit at the dinner table.

Cognitive Impairment in Multiple Sclerosis Tied to Diet

Mediterranean diet was strongest predictor of better cognitive scores

FDA APPROVED omaveloxolone (Skyclarys) over a photo of a man with Friedreich鈥檚 ataxia in a wheelchair outside.

First Treatment Approved for Rare Neurodegenerative Disorder

Omaveloxolone gets FDA nod for Friedreich's ataxia

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