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General Neurology

News, opinions and meeting coverage in neurology.

A photo of a male cardiac surgeon performing catheter ablation on a patient with atrial fibrillation

RF Ablation or Drugs for Afib: Choice May Matter for Cognitive Outcomes

New study suggests one does a better job of protecting the brain

A 3D printed covid spike protein in front of a 3D printed COVID virus.

SARS-CoV-2 Spike Protein Accumulates in the Skull and Brain

Whether findings have implications for long COVID is unclear

A photo of prescription bottles of pain medication sitting on the edge of a bathroom sink.

Chronic Pain Affects 21% of Americans, CDC Reports

Nearly 7% have pain severe enough to restrict daily activities

A photo of blue rubber gloved hands holding an assay plate.

Parkinson's Biomarker Shows High Accuracy

Assay identifies hallmark protein and could help diagnose people earlier

A photo of a male physician listening to his female patient.

Functional Neurological Disorder May Still Carry Stigma

FND is a feminist issue, researchers and clinicians maintain

Prepare for the Worst, Hope for the Best

Pediatric neurologist braces himself for worst case scenario

A photo of a mother holding her baby who suffers from microcephaly

Brain Injury Seen in Two Neonates Whose Mothers Had COVID

Infants were born early in the pandemic, before COVID vaccines were available

A computer rendering of a CAR-T cell attacking a cancer cell.

CAR T-Cell Therapy Feasible, Safe in Advanced Neuroblastoma

ORR of 63% with GD2-targeting product in kids with relapsed, refractory high-risk disease

Neuro Break over a computer rendering of neurons.

Detecting Alzheimer's in Speech; Manipulating CSF in Humans; Gut Microbiome and MS

News and commentary from the world of neurology and neuroscience

A computer rendering of of amyloid plaques affecting neurons and neurofibrillary tangles inside neurons

Brains Shrink With Anti-Amyloid Alzheimer's Drugs

Treatments accelerate brain atrophy, but reasons why remain a mystery

A medical illustration of the concept of circadian rhythm with a cut away human looking at the sun

Cluster Headache, Migraine Linked to Circadian System

Findings may influence treatment approaches for some patients

A photo of Tamia Potter

Potter Will Be Vanderbilt's First Black Female Neurosurgery Resident

A first since neurosurgery program opened in 1932

A photo of two bottles of Wakix tablets, 4.5 mg and 17.8 mg, and their packaging.

Pitolisant Safe and Effective in Children With Narcolepsy

First study in a pediatric population, with findings similar to adults

A computer rendering of covid viruses around a human brain

Functional Neurological Disorder Emerges After COVID Infection, Vaccines

Long COVID functional manifestations differ from post-vaccine effects

A photo of a female psychologist evaluating a little boy with autistic behaviors.

Autism Prevalence Is Up, CDC Report Shows

But early evaluations in young children started to fall as pandemic set in

FDA APPROVED tofersen over a computer rendering of a damaged motor neuron.

FDA Panel Supports Tofersen for Rare Genetic ALS

In a first, agency advisors back neurofilament light as a surrogate endpoint

FDA ADCOMM tofersen over a computer rendering of a damaged motor neuron.

Investigational ALS Drug May Have Clinical Benefit, FDA Staff Says

Neurofilament light will be evaluated as a surrogate endpoint in tofersen review

A photo of a young female physician standing at the bedside of her senior female patient.

Post-Op Delirium Linked to Accelerated Cognitive Decline

Cognitive trajectory showed consistent pattern for most of 6-year follow-up

AAOS over a photo of the Venetian Sands Expo Center in Las Vegas, Nevada.

More Data Suggest Concussion Raises Leg Injury Risk

Causality still unclear but getting harder to argue against

MRI images of the fetus inside the infant鈥檚 skull next to photos of the fetus removed.

Fetus Removed From Brain of 1-Year-Old Girl

Intracranial fetus-in-fetu identified in child with motor delay

A photo of a man laying on a gurney attached to a temperature management system.

Longer Temperature Management No Better After Cardiac Arrest

Device-based fever prevention beyond 36 hours shows no mortality or disability benefits

A photo of a pregnant woman laying on the couch blowing her nose.

Study Reassures on Asthma Med Use in Pregnancy and Kids' Neuropsych Risks

Use of leukotriene-receptor antagonists not tied to risks of ADHD, autism, Tourette syndrome

A photo of a worried-looking senior woman sitting at a table next to a window.

Incident Cognitive Impairment Tied to Stress

More than one in five older adults report high levels of perceived stress

A photo of a Houston Texans football player injured on the field.

NFL Concussion Symptoms Tied to Cognitive Function Decades Later

Players with concussion symptoms performed worse on cognitive tests as they aged

A photo of a man in a wheelchair showing his wife his phone as they sit at the dinner table.

Cognitive Impairment in Multiple Sclerosis Tied to Diet

Mediterranean diet was strongest predictor of better cognitive scores

FDA APPROVED omaveloxolone (Skyclarys) over a photo of a man with Friedreich鈥檚 ataxia in a wheelchair outside.

First Treatment Approved for Rare Neurodegenerative Disorder

Omaveloxolone gets FDA nod for Friedreich's ataxia

A close up of bottles of vitamin D supplements on a pharmacy shelf.

Lower Dementia Incidence Linked With Vitamin D Supplements

But large observational study has significant limitations

A computer rendered cutaway view of the respiratory syncytial virus

FDA Flags Potential Guillain-Barre Risk With RSV Vaccine Candidates

Both vaccines demonstrated high efficacy against symptomatic illness in large phase III trials

An example of artwork produced by a person with frontotemporal dementia. Credit: UCSF Memory and Aging Center

Frontotemporal Dementia Sparks Visual Creativity Early in Disease Course

Disinhibited region in the dorsal occipital cortex may play a role

A photo of Bruce Willis

Bruce Willis' Frontotemporal Dementia

The actor's family released an update detailing his new diagnosis

A photo of factories belching white smoke in a hazy sky

Nationwide Study Links Parkinson's Disease to Air Pollution

Researchers identify a hot spot in the Mississippi-Ohio River Valley

A graphical illustration of a focused ultrasound ablation of the brain.

Advanced Parkinson's Symptoms Improved With Focused Ultrasound

Pivotal trial shows 3-month improvement, but longer study is needed

A photo of a young adult male sitting in his apartment looking at an MRI of his brain.

Man Presents With Episodic, One-Sided Facial Paralysis

Uncommon presentation of MS detailed in case report

A computer rendering of a transparent brain filled with covid viruses.

Brain Structure, Widespread Connectivity Changes Seen With Long COVID

Gray matter atrophy, hyperconnectivity in patients with anxiety, depression

A photo of a dissected brain affected by Alzheimer's disease.

We May Be Better at Fending Off Dementia, Autopsies Suggest

Neurodegeneration pathologies look similar across birth epochs as dementia incidence declines

A computer rendering of a transparent body with the cervical spinal cord highlighted.

Spinal Stimulation Opens Door to Treating Stroke Survivors With Partial Paralysis

Recovery of strength, functional movements seen in pilot study

A computer rendering of a transparent skull with the brain and a covid virus highlighted.

Long COVID or Functional Neurological Disorder?

Neurologic symptoms in long COVID insufficiently studied, systematic review suggests

Neuro Break over a computer rendering of neurons.

Epstein-Barr/MS Link; How CBD Curtails Seizures; NIH Finds Rare Neurologic Disease

News and commentary from the world of neurology and neuroscience

A photo of a young physician talking to his senior male patient in his office.

There's No 'Recipe' to Reduce Dementia Risk -- Yet

Until more evidence emerges, here's how to discuss it with patients

SMFM over a photo of Moscone West in San Francisco, California

No Negative Neurodevelopmental Issues With Late Exposure to Antenatal Steroids

Follow-up to ALPS trial offers reassuring results for late preterm corticosteroids

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