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Endocrinology

News, opinions and meeting coverage in endocrinology.

Bed Rest in Pregnancy Raises Diabetes Risk

CHICAGO -- Women who are prescribed long-term bed rest for troubled pregnancies are at increased risk of developing gestational diabetes, researchers said here.

Hypoglycemia at Night Tied to Arrhythmias

Nocturnal hypoglycemia was a major risk factor for cardiac arrhythmias in type 2 diabetes patients who were already at an increased risk for cardiovascular events, according to British researchers.

Forget Glucometers, Use Voodoo Dolls Instead: That's Improbable!

A weekly report from our friends at Improbable Research.

Fatty Liver Tied to Diabetes, Atherosclerosis

LONDON -- Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of both type 2 diabetes and carotid atherosclerosis, according to two studies presented here at the annual meeting of the European Association for the Study of the Liver.

Do Fat Teens Face an Early Death?

Life expectancy gains seen over the last half-century do not appear to extend to adults who were overweight or obese in adolescence, according to a large study spanning several decades.

FDA Panel Says Yes to Inhaled Insulin Device

HYATTSVILLE, Md. -- An FDA advisory panel has voted in favor of approving a new inhaled insulin device, Afrezza, as a short-acting treatment to improve glycemic control in both type 1 and type 2 diabetes.

ACC: Metformin No Help in MI Recovery

WASHINGTON -- Metformin started soon after reperfusion in the acute setting didn't help cardiac function recover in nondiabetic heart attack patients, a trial showed.

Small, Frequent Meals Don't Rev Metabolism

Dieters are often told to eat small, frequent meals instead of two or three bigger meals a day to shed extra pounds, but eating this way does not boost metabolism and may increase cardiovascular disease risk, researchers found.

Higher BMI May Be Better for Older Adults

Adults over 65 at the high end of the healthy body mass index range were at lower risk of mortality, and those at the low end were at highest risk, according to a recent meta-analysis.

Abbott Continues Glucose Meter Recall

Abbott Diabetes Care is continuing its recall of FreeStyle and FreeStyle Flash blood glucose meters because of the potential for erroneous low blood sugar readings, the company said.

Vitamin D Blog: Cutting Edema in Athletes' Bones

Vitamin D supplementation might help professional athletes who are being treated for bone marrow edema with bisphosphonates, according to a new study.

FDA OKs Northera for Hypotension

The FDA has approved droxidopa (Northera) for the treatment of neurogenic orthostatic hypotension, a rare disease that results in a drop in blood pressure when patients try to stand up.

Tamoxifen Found in Bodybuilding Supplement

British researchers have found tamoxifen in supplements used by bodybuilders -- an active ingredient that isn't clearly labeled on the bottle.

Levoxyl Returns, But Will Patients Switch Back?

After being recalled about a year ago for unusual odors, Levoxyl is set to come back on the market in March, but clinicians may not be inclined to switch back, some experts said.

New Guideline Lowers eGFR for Dialysis Start

New Canadian guidelines suggest that nephrologists can wait to start dialysis in some chronic kidney disease patients until their estimated glomerular filtration rate drops below the 10 to 12 mL/min now commonly used.

Tandem Expands Leaky Insulin Cartridge Recall

Tandem Diabetes has expanded a recall of insulin cartridges for its t:slim Insulin Pump that run the risk of leaking, the company said in a statement.

Bodybuilders Bulk Up Using ... Cancer Drugs?

While steroids are all-stars among performance-enhancing drugs, breast cancer drugs are a lesser-known staple of doping regimens, as are some investigational agents that aren't available on any regulated market.

11 Endocrinology Apps for Docs' Toolboxes

Even if endocrinologists aren't already suggesting smartphone apps to their patients, they've likely been asked to offer up recommendations. Here's a list of 11 apps you should know about.

FDA Rules Differ for OTC vs. POC Glucose Monitors

The FDA has released two draft guidances that establish a line between over-the-counter and point-of-care blood glucose monitors.

Colonoscopies: The Longer the Better

Polyp and adenoma detection rates were highest when the colonoscopy withdrawal time was 9 minutes long, near the upper limit of the recommended 6 to 10 minutes withdrawal time, researchers found.

10 Questions: Rep. Phil Gingrey, MD (R-Ga.)

If you could change one thing about the healthcare system, what would it be? Eliminate Obamacare, says Rep. Phil Gingrey, MD (R-Ga.). That's his answer to just one of the 10 Questions the 麻豆传媒 staff is asking leading clinicians, researchers, and leaders in their community to get their personal views on their chosen profession. In this series we share their uncensored responses.

Testosterone Level Affects Flu Shot Response

Men with high testosterone and a certain genetic cluster may not experience an antibody response after a flu shot, researchers suggested -- a finding that could affect men taking prescription testosterone.

OTC Thyroid 'Boosters' May Harm

Patients who take over-the-counter supplements that promise to enhance thyroid function may get more than they bargained for, endocrinologists warn.

Antidepressant Dressed Up for Menopause

One drug company can now brag about a nonhormonal option for menopausal hos flashes. But Brisdelle is just an old drug dressed up in a new feminine name and packaging -- it's the antidepressant paroxetine, better known by its brand name, Paxil.

B12 Deficiency Tied to Reflux Medications

Vitamin B12 deficiency is significantly more likely among patients taking prescription medications for gastroesophageal reflux disease, researchers found.

Diabetes: TAVI Trumps Heart Surgery

Patients with diabetes who had aortic stenosis fared better in terms of mortality and kidney function during the first year if they underwent transcatheter aortic valve implantation (TAVI) rather than surgery, a post-hoc analysis found.

Gastric Artery Embolization Tied to Weight Loss

CHICAGO -- Embolization of the left gastric artery was associated with significant weight loss compared with that seen in patients who underwent a control procedure, researchers found.

Post-Menopause Brain Drain Tied to Progesterone

Estrogen levels after menopause may have no impact on cognitive function, but progesterone levels might, researchers found.

Bone Density Higher in Blacks, Vitamin D Lower

Black Americans had lower levels of total 25-hydroxyvitamin D and vitamin D-binding protein than whites, but similar levels of bioavailable 25-hydroxyvitamin D, and higher bone density.

Testosterone Levels: Middle Range Best in Old Age

Older men whose natural testosterone levels were in the middle range tended to live longer than those with the highest and lowest levels, a study found.

Surgery Beats Medical Tx for Diabetes 'Cure'

ATLANTA -- Bariatric surgery's beneficial effects for type 2 diabetes were significantly greater than even the most rigorous medical and lifestyle interventions, a researcher said here.

Combo Angiotensin Tx Ups Kidney Risks

ATLANTA -- In yet another trial, dual blockade of the renin-angiotensin system (RAAS) didn't slow progression of kidney disease in diabetic patients and carried a higher risk of serious adverse events compared with monotherapy, researchers reported here.

Combo Drug Qsymia Tops for Weight Loss

Overweight people who took the phentermine/topiramate combination diet drug Qsymia lost more weight than people taking a placebo or either drug alone in an industry-funded study.

Hyperthyroid Drugs Tied to Birth Defects

SAN JUAN -- Two of the most commonly used drugs for treating hyperthyroidism were linked to birth defects when used in early pregnancy, though they have differing effects, researchers reported here.

TSH Suppression: More Harm Than Good After Cancer Surgery?

SAN JUAN -- Suppressing thyroid-stimulating hormone (TSH) after thyroidectomy for low-risk cancer increases the risk of osteoporosis in women without cutting back on cancer recurrence, researchers reported here.

Daytime Snoozing May Tell Risk of Hypoglycemia

Older patients with diabetes who are overly tired during the day may be at a higher risk for hypoglycemia, researchers reported.

Effects of Early Puberty in Girls Persist as Adults

Women with a history of idiopathic precocious puberty had increased rates of clinical hyperandrogenism, but fertility was normal in adulthood among those who had been treated for the condition, a cross-sectional study found.

Low E Not Low T May Be the Problem

Some symptoms traditionally attributed to low testosterone may actually be due to estrogen deficiency, researchers found.

In Some Patients Metformin Impairs Thinking

The widely acclaimed diabetes drug metformin was linked with impaired brain function in patients who took the drug, although supplementation with vitamin B12 may alleviate metformin-induced deficiencies, according to new research.

Baldness Drug May Depress Sperm Count

Men men using finasteride to treat baldness had a dramatic increase in sperm count following discontinuation of the drug, according to a review of records at a male infertility clinic.

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