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Endocrinology

News, opinions and meeting coverage in endocrinology.

DSM-5: What's In, What's Out

PHILADELPHIA -- Reports here provided what may be the last public update on DSM-5, the next edition of American psychiatry's diagnostic guide, before it is formally released in May 2013.

OTC Bug Bite Remedies of Little Help

Treating simple bug bites isn't usually necessary and there's little evidence to support doing so, a review warned.

Doctors Say 45 Common Tests 'Overused'

Nine specialty groups have listed tests and treatments that are frequently overused, such as antibiotics for sinus attacks and CT scans for low back pain, in the first phase of a long-term project.

FDA Adds More Warnings for Lipitor, Crestor, and Zocor

WASHINGTON -- Statins may cause drug-drug interactions for patients taking drugs to treat HIV/AIDS or hepatitis C, according to a new statin warning from the FDA.

FDA Adds Diabetes Warning to Statin Label

WASHINGTON -- The FDA is changing the labeling on statins to include a warning about increased risks of hyperglycemia and transient memory problems, but the agency is no longer recommending routine liver function testing.

Diabetes Expert Disses Weight-Loss Programs

WASHINGTON -- Community-based weight-loss programs have not been shown to be effective at reducing the incidence of diabetes, so implementing a national program would likely be money down the drain, a diabetes expert said at a symposium on Tuesday.

Fructose No Substitute for Glucose in Diabetes

NEW YORK -- Although it negates the dumping of glucose directly into the bloodstream, fructose may not be the choice sweetener for diabetics, researchers said here.

RSNA: Growth Hormone May Help Heavy Women With Bone Problems

CHICAGO -- Premenopausal women who are obese may not be spared from osteopenia, as some research has suggested, but growth hormone therapy may help spur bone formation, researchers said here.

Readers Say Vitamin Levels Should Be Checked Yearly

Processed foods, mineral-depleted soil, overcooked vegetables, increased stress levels -- all of these increase the chances of having a vitamin deficiency, according to a vocal majority of 麻豆传媒 readers who commented on last week's poll.

EASD: Gestational Diabetes Guidelines Controversial

LISBON -- International guidelines on screening for gestational diabetes that will likely raise the prevalence of the condition have sparked questions over appropriate diagnostic tools and cost efficacy, researchers said here.

Cancer Risk Forces Actos Off French, German Markets

Drug regulators in Germany and France have ordered doctors to stop prescribing the type 2 diabetes drug pioglitazone (Actos), following a French study suggesting a heightened risk of bladder cancer.

IUD Safe Right After Abortion

Women undergoing an abortion can have an intrauterine device (IUD) safely placed immediately after the procedure, with similar rates of expulsions and other complications, a randomized trial found.

ASCO: Flaxseed No Help for Hot Flashes

CHICAGO -- Flaxseed will not ease hot flashes for women with menopausal symptoms or breast cancer survivors taking anti-estrogen drugs, according to clinical trial results.

15 Eggs Magic Number for Best Results in IVF

The odds of achieving a live birth after in vitro fertilization (IVF) increased steadily with the number of eggs retrieved after ovarian stimulation, topping out at about 15, data from a large IVF registry showed.

SID: No Skin Cancer Risk Seen With Prednisone

PHOENIX -- Use of systemic corticosteroids did not increase the risk of nonmelanoma skin cancer in a prospective study, contradicting previous evidence from several retrospective studies, investigators reported here.

Diet, Exercise Sufficient to Reduce Triglycerides

While cholesterol control is often balanced between statins and lifestyle changes, reducing triglycerides can usually be accomplished with diet and lifestyle changes alone, according to a new scientific statement from the American Heart Association.

FDA Approves Testosterone Gel Applied to Thigh

A topical testosterone gel designed to be applied to the upper leg has won FDA approval for use by testosterone-deficient men, its manufacturer said.

Take Rosiglitazone Off the Market, Says FDA Staff

WASHINGTON -- Rosiglitazone (Avandia) should be pulled from the market because of the "serious" cardiovascular risk the diabetes drug poses, which exceeds that of competitor pioglitazone (Actos), FDA staff reviewers again recommended.

ACC: Triglycerides Decreased with Rosuvastatin Therapy

ATLANTA -- In a study that specifically scrutinized the effects of statin therapy on triglycerides, researchers said that rosuvastatin (Crestor) significantly reduced the blood lipid that has been linked to coronary artery disease better than placebo.

ACC: FDA Announces Review of ACCORD Data

ATLANTA -- The FDA said it will conduct a full review of findings from a study which concluded that neither aggressive lipid-lowering therapy nor tight blood pressure control reduced cardiovascular events in persons with diabetes.

Stinky Diabetes Drug May Result in Poor Adherence

An immediate-release form of the antidiabetic agent metformin has a dead fish odor that may cause patients to stop taking the drug, clinicians warned.

Down a Beer to Improve Bone Health? Not So Fast

A flagon of ale may indeed be a good source of dietary silicon, a recent study showed, but experts say any attempt to link beer drinking to bone health is not based on scientific data.

SSRIs Affect Breast Milk Production

Women taking selective serotonin reuptake inhibitor antidepressants may experience delays in postpartum milk production, researchers said.

The Top 10 Medical Advances of the Decade

From genome to hormones, doctors pick the top medical advances of the decade.

FDA Finds Oral Insulin Spray Safe for IND Use

The FDA approved Oral-lyn, an insulin spray treatment for type I and type II diabetes, for its Investigational New Drug program.

Kidney Disease Raises Risk of Hypoglycemia

WHEELING, W.Va. -- Dangerous hypoglycemic episodes are a significant risk for patients with chronic kidney disease, whether they have diabetes or not, researchers said.

Osteoporosis Drug Speeds Fracture Healing

TORONTO -- A drug for severe osteoporosis has an unexpected side effect, researchers found -- it appears to speed healing of hard-to-mend bone fractures.

Dizziness Linked to Bone Health

SEONGNAM, South Korea -- Low bone mineral density may increase the risk of benign positional vertigo, researchers found.

Weight-Loss Trial Final Report: 52 Pounds of Fat Melted Away

WEST PALM BEACH, Fla. -- The official results are in: My ending weight was 231 pounds -- a loss of 52 pounds from my starting weight of 283 pounds in January 2008.

RSNA: Dry-Needling Plus Steroid Effective for Plantar Fasciitis

CHICAGO -- For patients with plantar fasciitis, a notoriously difficult condition to treat, an Italian team has come up with a novel approach that uses dry-needling combined with a steroid injection, researchers said here.

Recall of Three Little Words Helps Quick Diagnosis of Mild Cognitive Impairment

ATLANTA -- Mild cognitive impairment can be determined in less than five minutes with a three-word memory test and a clock- drawing task, according to researchers here. The words are apple, penny, and table.

Pregnancy Risks Differ for Interracial Couples

STANFORD, Calif. -- The risk for some pregnancy complications may be greater when one partner is white and the other Asian, researchers found.

Normal Enzyme Levels May Hide Advanced Liver Fibrosis

MILAN, Italy -- Patients with nonalcoholic fatty liver disease but normal alanine aminotransferase (ALT) levels are still at risk of severe hepatic disease, researchers found.

Herpes Virus Linked to Ketosis-Prone Diabetes

PARIS -- A herpes virus is associated with an atypical form of type 2 diabetes found in people of African origin, researchers said here.

Excess Weight Unlikely to Be 'Glandular Problem'

LEXINGTON, Ky. -- Correcting the hormonal deficit caused by hypothyroidism did not trigger significant weight loss in children with acquired hypothyroidism.

Boxed Heart Failure Warning Added to Two Diabetes Drugs

ROCKVILLE, Md. -- The makers of rosiglitazone (Avandia) and pioglitazone (Actos), have agreed to add a black box warning to the type 2 diabetes drugs' labels about an increased risk of heart failure, the FDA said today.

ASCO: Five Years of Arimidex Causes Bone Loss

ATLANTA 芒鈧€� Five years of breast cancer adjuvant therapy with an aromatase inhibitor, can lead to a 6% to 7% loss of bone mineral density, a trigger for osteoporosis for women who are borderline osteopenic when they begin treatment, investigators reported here.

High-Dose Steroids Linked to Risk of Atrial Fibrillation

ROTTERDAM, The Netherlands 芒鈧€� High dose corticosteroid therapy may increase the risk of atrial fibrillation, researchers here reported.

Estrogen Alone Does Not Increase Risk of Breast Cancer

STANFORD, Calif. - Post-menopausal women who took estrogen alone for more than seven years did not have an increased risk of breast cancer, according to a study of more than 10,000 women ages 50 to 79. The data were dramatically different from a sister study stopped in 2002 of estrogen plus progestin.

Pediatricians Say Most U.S. Kids Don't Get Enough Calcium

ELK GROVE, Ill. - Most U.S. children don't get enough calcium in their diets, and pediatricians should intervene to help remedy the problem, according to guidelines issued today by the American Academy of Pediatrics.

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